(R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL

Base Information

• Chemical Name: (R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL
• CAS No.: 372967-45-8
• Molecular Formula: C₁₉H₂₅NO
• Molecular Weight: 283.414
• Mol file: 372967-45-8.mol

Synonyms:(R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL;N,N-DIBENZYL-D-VALINOL;(R)-2-(DIBENZYLAMINO)-3-METHYLBUTAN-1-OL

Chemical Property of (R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL

Chemical Property:

• PSA: 23.47000
• LogP: 3.70570

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL

There total 14 articles about (R)-2-(DIBENZYLAMINO)-3-METHYL-1-BUTANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

→ N,N-dibenzylvalinol (111060-54-9,372967-45-8)

Guidance literature:

Reference yield: 91.0%

(S)-valinol (2026-48-4,473-75-6) + benzyl bromide (100-39-0) → N,N-dibenzylvalinol (111060-54-9,372967-45-8)

Guidance literature:

With potassium carbonate; In ethanol; for 24h; Ambient temperature;

DOI:10.1039/a707937k DOI:10.1016/S0957-4166(98)00344-9

Reference yield: 75.0%

(S)-benzyl 2-(dibenzylamino)-3-methylbutanoate (111060-51-6) → N,N-dibenzylvalinol (111060-54-9,372967-45-8)

Guidance literature:

With C₃₃H₂₉FeMnN₂O₃P; hydrogen; potassium carbonate; In isopropyl alcohol; at 110 ℃; for 16h; under 37503.8 Torr; Autoclave;

DOI:10.1021/acs.orglett.8b00864

upstream raw materials:

D,L-valine

benzyl bromide

(S)-2-dibenzylamino-3-methylbutanoic acid

(S)-valinol

Downstream raw materials:

(4R,5S)-5-Dibenzylamino-4-hydroxy-6-methyl-hept-2-ynoic acid ethyl ester

(4S,5S)-5-Dibenzylamino-4-hydroxy-6-methyl-hept-2-ynoic acid ethyl ester

(1S,2S)-1-chloro-3-methyl-1-phenylbutan-2-amine

(1R,2S)-1-chloro-3-methyl-1-phenylbutan-2-amine