1,3,7,7-Tetramethylnorbornan-2-one

Base Information

• Chemical Name: 1,3,7,7-Tetramethylnorbornan-2-one
• CAS No.: 5811-48-3
• Molecular Formula: C₁₁H₁₈O
• Molecular Weight: 166.263
• Mol file: 5811-48-3.mol

Synonyms:1,3,7,7-Tetramethylbicyclo[2.2.1]heptan-2-one;1,3,7,7-Tetramethylnorbornan-2-one;3-Methylcamphor

Chemical Property of 1,3,7,7-Tetramethylnorbornan-2-one

Chemical Property:

• Boiling Point: 95 - 96 °C (11 mmHg)
• PSA: 17.07000
• LogP: 2.64770

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3,7,7-Tetramethylnorbornan-2-one

There total 10 articles about 1,3,7,7-Tetramethylnorbornan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (464-49-3,68546-28-1) + methyl iodide (74-88-4) → (1R,4R)-1,3,7,7-tetramethylbicyclo[2.2.1]heptan-2-one (5811-48-3,51100-01-7,93602-40-5,93602-41-6,135683-80-6,135683-86-2)

Guidance literature:

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one; With lithium diisopropyl amide; In tetrahydrofuran; at 20 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at 120 ℃; for 20h; Sealed tube;

Reference yield:

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (464-49-3,68546-28-1) + methyl iodide (74-88-4) → (1R,4R)-1,3,7,7-tetramethylbicyclo[2.2.1]heptan-2-one (5811-48-3,51100-01-7,93602-40-5,93602-41-6,135683-80-6,135683-86-2) + L-(-)-fenchone (139346-46-6)

Guidance literature:

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at 100 ℃; for 22h; Sealed tube;

Reference yield:

→ (1R,4R)-1,3,7,7-tetramethylbicyclo[2.2.1]heptan-2-one (5811-48-3,51100-01-7,93602-40-5,93602-41-6,135683-80-6,135683-86-2)

Guidance literature:

With potassium carbonate; im geschlossenen Rohr;

DOI:10.1007/s004100100289

upstream raw materials:

(1R)-3-((E)-chloromethylene)-1,7,7-trimethyl-norbornan-2-one

4,7,7-trimethyl-3-oxo-norbornane-2-carbonitrile

methyl iodide

(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

Downstream raw materials:

(1R)-1,3,7,7-tetramethyl-norbornan-2-one oxime