Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester

Base Information

• Chemical Name: Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester
• CAS No.: 871555-75-8
• Molecular Formula: C14H9ClF3NO2
• Molecular Weight: 315.679
• Mol file: 871555-75-8.mol

Synonyms:Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester;phenyl 4-chloro-3-(trifluoromethyl)phenylcarbamate

Chemical Property of Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester

Chemical Property:

• PSA: 38.33000
• LogP: 5.04270

Purity/Quality:

99.0% Min ^*data from raw suppliers

Phenyl(4-chloro-3-(trifluoromethyl)phenyl)carbamate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester

There total 2 articles about Carbamic acid,N-[4-chloro-3-(teifluoromethyl)phenyl]-,phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenyl chloroformate (1885-14-9) + 4-chloro-3-trifluoromethyl-aniline (320-51-4) → (4-chloro-3-trifluoromethylphenyl)carbamic acid phenyl ester (871555-75-8)

Guidance literature:

With triethylamine; In dichloromethane; at 5 - 20 ℃; for 2h;

Reference yield:

→ (4-chloro-3-trifluoromethylphenyl)carbamic acid phenyl ester (871555-75-8)

Guidance literature:

Reference yield: 98.5%

ethyl 4-(4-aminophenoxy)picolinate + (4-chloro-3-trifluoromethylphenyl)carbamic acid phenyl ester (871555-75-8) → C22H17ClF3N3O4

Guidance literature:

With triethylamine; In dimethyl sulfoxide; at 20 ℃; Inert atmosphere;

upstream raw materials:

phenyl chloroformate

4-chloro-3-trifluoromethyl-aniline

Downstream raw materials:

1-(3-Trifluormethyl-4-chlor-phenyl)-5-imino-4,4-dimethyl-2-imidazolidinon

4-[ ({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenol

sorafenib

4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)-3-fluorophenoxy)-2-(N-1',1',1'-trideuteromethyl)pyridine amide

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