Phenyl chloroformate

Base Information Edit

Chemical Name:Phenyl chloroformate
CAS No.:1885-14-9
Deprecated CAS:180273-50-1,1404060-48-5
Molecular Formula:C7H5ClO2
Molecular Weight:156.569
Hs Code.:2915.13 Oral rat LD50: 1410 ul/kg
European Community (EC) Number:217-547-8
ICSC Number:1007
NSC Number:210946
UN Number:2746
UNII:6TND0D6D3Y
DSSTox Substance ID:DTXSID9044403
Nikkaji Number:J33.963F
Wikidata:Q16760605
Mol file:1885-14-9.mol

Synonyms:phenyl chloroformate

Suppliers and Price of Phenyl chloroformate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Phenyl chloroformate
100g
$ 319.00

TRC
Phenyl chloroformate
250g
$ 330.00

TRC
Phenyl chloroformate
50g
$ 120.00

TRC
Phenyl chloroformate
100g
$ 165.00

TCI Chemical
Phenyl Chloroformate >98.0%(GC)(T)
500mL
$ 92.00

TCI Chemical
Phenyl Chloroformate >98.0%(GC)(T)
25mL
$ 17.00

TCI Chemical
Phenyl Chloroformate >98.0%(GC)(T)
100mL
$ 29.00

SynQuest Laboratories
Phenyl chloroformate 98.5%
100 g
$ 20.00

SynQuest Laboratories
Phenyl chloroformate 98.5%
500 g
$ 70.00

Sigma-Aldrich
Phenyl chloroformate 99%
100g
$ 70.40

Total 103 raw suppliers

Chemical Property of Phenyl chloroformate Edit

Chemical Property:

Appearance/Colour:colorless liquid with a strong odor
Vapor Pressure:1.22 psi ( 20 °C)
Melting Point:-28 °C
Refractive Index:1.5110
Boiling Point:186.5 °C at 760 mmHg
Flash Point:79 °C
PSA：26.30000
Density:1.283 g/cm³
LogP:2.42420
Storage Temp.:Refrigerator
Sensitive.:Moisture Sensitive
Solubility.:Miscible with N,N-dimethylformamide.
Water Solubility.:hydrolysis
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:155.9978071
Heavy Atom Count:10
Complexity:119
Transport DOT Label:Poison Corrosive

Purity/Quality:

99% ^*data from raw suppliers

Phenyl chloroformate ^*data from reagent suppliers

Safty Information:

Pictogram(s): T+
Hazard Codes:T+
Statements: 22-26-34-41-38-29-37
Safety Statements: 26-28-36/37/39-45-28A

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Toxic Gases & Vapors -> Acid Halides
Canonical SMILES:C1=CC=C(C=C1)OC(=O)Cl
Inhalation Risk:A harmful contamination of the air will be reached quickly on evaporation of this substance at 20 °C.
Effects of Short Term Exposure:The substance is corrosive to the eyes and respiratory tract. The substance is severely irritating to the skin. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema, but only after initial corrosive effects on eyes and/or airways have become manifest. The effects may be delayed.
Uses Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.

Technology Process of Phenyl chloroformate

There total 30 articles about Phenyl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.5%