1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane

Base Information

• Chemical Name: 1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane
• CAS No.: 345612-63-7
• Molecular Formula: C₁₈H₃₆N₈O₄
• Molecular Weight: 428.535
• Hs Code.: 2933990090
• Mol file: 345612-63-7.mol

Synonyms:1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane;1,4,8,11-Tetraazacyclotetradecane-N,N',N'',N'''-tetraacetamide, min. 98%;1,4,8,11-Tetraazacyclotetradecane-N,N',N",N''-tetraacetaMide,Min.98%;1,4,8,11-Tetraazacyclotetradecane-N,N',N'',N'''-tetraacetamide

Chemical Property of 1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane

Chemical Property:

• Vapor Pressure: 4.03E-23mmHg at 25°C
• Boiling Point: 762°C at 760 mmHg
• Flash Point: 414.6°C
• PSA: 185.32000
• Density: 1.17g/cm³
• LogP: -1.51780
• Sensitive.: Hygroscopic

Purity/Quality:

99% ^*data from raw suppliers

1,4,8,11-Tetraazacyclotetradecane-N,N',N'',N'''-tetraacetamide, min. 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane

There total 2 articles about 1,4,8,11-Tetrakis(aminocarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1,4,8,11-Tetraazacyclotetradecane (295-37-4) + bromo-acetic acid amide (683-57-8) → 1,4,8,11-tetrakis(carbamoylmethyl)-1,4,8,11-tetraazacyclotetradecane (345612-63-7)

Guidance literature:

With sodium hydroxide; In water; at 20 - 80 ℃; for 4.25h; pH=10 - 11;

DOI:10.1021/ja307909x

Reference yield:

C16H32N8NiO4(2+) → 1,4,8,11-tetrakis(carbamoylmethyl)-1,4,8,11-tetraazacyclotetradecane (345612-63-7)

Guidance literature:

With disodium hydrogenphosphate; 3-(trimethylsilyl)-1-propanesulfonic acid,sodium salt; potassium carbonate; sodium chloride; at 37 ℃; pH=7.7;

DOI:10.1021/ja307909x

upstream raw materials:

1,4,8,11-Tetraazacyclotetradecane

bromo-acetic acid amide

Refernces

• 1、 -. "MACROCYCLES, COBALT AND IRON COMPLEXES OF SAME, AND METHODS OF MAKING AND USING SAME". Page/Page column 52. . Retrieved 2015/03/28.