1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl

Base Information

Chemical Name:1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl
CAS No.:1357259-50-7
Molecular Formula:C7H8BrClN2O
Molecular Weight:215.049
Hs Code.:
Mol file:1357259-50-7.mol

Synonyms:1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl;1-(3-Amino-5-bromopyridin-2-yl)ethanone

Suppliers and Price of 1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl

There total 4 articles about 1-(3-aMino-5-broMopyridin-2-yl)ethanone hcl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1160936-52-6
1-(5-bromo-3-fluoropyridin-2-yl)ethan-1-one

: 1357259-50-7
1-(3-amino-5-bromopyridin-2-yl)ethan-1-one

Guidance literature:: With dimethoxybenzylamine; In N,N-dimethyl-formamide; at 120 ℃; for 0.5h; Microwave irradiation;
DOI:10.1021/acsmedchemlett.6b00232

Reference yield:

: 1357259-49-4
C₁₆H₁₇BrN₂O₃

: 1357259-50-7
1-(3-amino-5-bromopyridin-2-yl)ethan-1-one

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 0.5h;

Reference yield:

: 573675-25-9
5-bromo-3-nitropyridine-2-carbonitrile

: 1357259-50-7
1-(3-amino-5-bromopyridin-2-yl)ethan-1-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrabutyl ammonium fluoride / N,N-dimethyl-formamide / 0.5 h / -15 °C / Molecular sieve

1.2: 1 h

2.1: toluene; diethyl ether / 1 h / -10 - 0 °C / Inert atmosphere

2.2: 18 h / 20 °C

3.1: N,N-dimethyl-formamide / 0.5 h / 120 °C / Inert atmosphere; microwave irradiation

4.1: trifluoroacetic acid / dichloromethane / 0.5 h

With tetrabutyl ammonium fluoride; trifluoroacetic acid; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;