1-(Piperidin-4-yl)propan-1-ol

Base Information

Chemical Name:1-(Piperidin-4-yl)propan-1-ol
CAS No.:24152-48-5
Molecular Formula:C₈H₁₇NO
Molecular Weight:143.229
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50596468
Mol file:24152-48-5.mol

Synonyms:1-Piperidin-4-ylpropan-1-ol;24152-48-5;1-(Piperidin-4-yl)propan-1-ol;1-(4-piperidyl)propanol;SCHEMBL28892;1-(4-Piperidinyl)-1-propanol;DTXSID50596468;WDOWPHYNSYXXHJ-UHFFFAOYSA-N;ZAA15248;MFCD09055257;AKOS006283514;SB41228;CS-16002;DA-18453;1-Piperidin-4-ylpropan-1-ol, AldrichCPR;CS-0083895;F52461;EN300-6759877

Suppliers and Price of 1-(Piperidin-4-yl)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-piperidin-4-ylpropan-1-ol
50mg
$ 45.00

Sigma-Aldrich
1-Piperidin-4-ylpropan-1-ol Aldrich
1g
$ 140.00

ChemBridge Corporation
1-piperidin-4-ylpropan-1-ol 95%
5 g
$ 297.00

American Custom Chemicals Corporation
1-PIPERIDIN-4-YLPROPAN-1-OL 95.00%
10G
$ 2771.14

American Custom Chemicals Corporation
1-PIPERIDIN-4-YLPROPAN-1-OL 95.00%
5G
$ 1722.11

American Custom Chemicals Corporation
1-PIPERIDIN-4-YLPROPAN-1-OL 95.00%
1G
$ 867.12

AK Scientific
1-Piperidin-4-ylpropan-1-ol
1g
$ 536.00

Total 6 raw suppliers

Chemical Property of 1-(Piperidin-4-yl)propan-1-ol

Chemical Property:

Vapor Pressure:0.0147mmHg at 25°C
Boiling Point:227.9°C at 760 mmHg
PKA:15.01±0.20(Predicted)
Flash Point:83.4°C
PSA：32.26000
Density:0.941g/cm³
LogP:1.08570
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:143.131014166
Heavy Atom Count:10
Complexity:89.3

Purity/Quality:

98% ^*data from raw suppliers

1-piperidin-4-ylpropan-1-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1CCNCC1)O

Technology Process of 1-(Piperidin-4-yl)propan-1-ol

There total 4 articles about 1-(Piperidin-4-yl)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1-(3-bromopyridin-4-yl)propan-1-ol

: 24152-48-5
1-(piperidin-4-yl)propan-1-ol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; at 80 ℃; for 18h; under 22502.3 Torr; Autoclave;
DOI:10.1002/ejoc.201900450

Reference yield:

: 1701-69-5
1-(4-pyridyl)-1-propanone

: 24152-48-5
1-(piperidin-4-yl)propan-1-ol

Guidance literature:: In chloroform; acetic acid;

Reference yield:

: 626-55-1,163928-56-1
3-Bromopyridine

: 24152-48-5
1-(piperidin-4-yl)propan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; 2,2,6,6-tetramethyl-piperidine / tetrahydrofuran; hexane / 0.42 h / -85 °C

1.2: 0.25 h / -85 °C

2.1: palladium 10% on activated carbon; hydrogen; triethylamine / methanol / 18 h / 80 °C / 22502.3 Torr / Autoclave

With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; palladium 10% on activated carbon; hydrogen; triethylamine; In tetrahydrofuran; methanol; hexane;
DOI:10.1002/ejoc.201900450