1701-69-5

Basic information

• Product Name: 4-PROPIONYLPYRIDINE
• Synonyms: 4-PROPIONYLPYRIDINE;4-PYRIDYL ETHYL KETONE;1-(4-pyridyl)-1-propanon;1-(4-pyridyl)-1-propanone;ethyl4-pyridylketone;ketone,ethyl4-pyridyl;1-(4-Pyridinyl)-1-propanone;1-(4-Pyridinyl)propane-1-one
• CAS NO: 1701-69-5
• Molecular Formula: C₈H₉NO
• Molecular Weight: 135.16
• Mol File: 1701-69-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 89-90°C 2mm
• Flash Point: 89-90°C/2mm
• Appearance: /
• Density: 1.034
• Vapor Pressure: 0.0684mmHg at 25°C
• Refractive Index: 1.5220
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 2.75±0.26(Predicted)
• BRN: 111366
• CAS DataBase Reference: 4-PROPIONYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PROPIONYLPYRIDINE(1701-69-5)
• EPA Substance Registry System: 4-PROPIONYLPYRIDINE(1701-69-5)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 24/25-39-26
• RTECS: UC3800000
• Hazardous Substances Data: 1701-69-5(Hazardous Substances Data)

Usage

General Description

4-Propionylpyridine is a chemical compound with the molecular formula C9H9NO. It is a derivative of pyridine and is commonly used as a flavoring agent in food products. The compound is often found in tobacco and is responsible for the characteristic smell of cigarette smoke. In addition, 4-propionylpyridine has been identified as a potential contributor to the addictive properties of nicotine, as it has been shown to enhance the reinforcing effects of the drug. Studies have also suggested that the compound may have neurotoxic effects, potentially contributing to the harmful effects of tobacco use. Overall, 4-propionylpyridine is a chemically significant compound with important implications for both flavor technology and public health.

InChI:InChI=1/C8H9NO/c1-2-8(10)7-3-5-9-6-4-7/h3-6H,2H2,1H3

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 925-90-6 ethylmagnesium bromide 
• 1570-45-2 isonicotinic acid ethylester 
• 105-37-3 Ethyl propionate 
• 23389-76-6 4-hydroxypropylpyridine 
• 872-85-5 pyridine-4-carbaldehyde 
• 7732-18-5 water 
• 1122-81-2 4-n-propylpyridine 
• 100377-32-0 N-methyl-N-methoxyisonicotinamide 
• 55-22-1 pyridine-4-carboxylic acid 
• 501072-26-0 4-(1-hydroxy-3-trimethylsilanyl-2-propynyl)pyridine 
• 1826-67-1 vinyl magnesium bromide 

Downstream Products

• 21816-40-0 1-[4]pyridyl-propan-1-one-phenylhydrazone 
• 129593-96-0 5-Methyl-6-(4-{N'-[1-pyridin-4-yl-prop-(E)-ylidene]-hydrazino}-phenyl)-4,5-dihydro-2H-pyridazin-3-one 
• 129593-92-6 6-(4-{N'-[1-Pyridin-4-yl-prop-(E)-ylidene]-hydrazino}-phenyl)-4,5-dihydro-2H-pyridazin-3-one 
• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 157371-07-8 (S)-1-(4'-pyridyl)-propanol 
• 24152-48-5 1-(piperidin-4-yl)propan-1-ol 
• 98377-51-6 4-Propionylpyridine oxime 
• 30235-28-0 4-pyridin-4-yl-thiazol-2-ylamine 
• 1610772-83-2 1-oxo-1-(pyridin-4-yl)propan-2-yl 4-methoxybenzoate 
• 1186195-22-1 4-(1,1-difluoropropyl)pyridine 
• 1187668-84-3 5-methyl-N-(3-methylphenyl)-4-(4-pyridinyl)-1,3-thiazol-2-amine 

Relevant articles and documents

Casein kinase 1 (CK1) inhibitor for plants (by machine translation)

[Problem] to provide various lead compounds PHA derivatives, and/or circadian rhythm control agent having stronger CK1 inhibitor activity. [Solution] a compound represented by formula I, or a salt thereof or a solvate thereof. (R1 The, H or C1 - 5 A straight-chain, branched or cyclic alkyl group, alkenyl group or alkynyl group, R2 The, H, halogen (F, Cl, Br or I), or a C1 - 4 The alkyl group, the ring A, 5 - 8 membered lactam ring showing; however, R1 And R2 Except H together. )[Drawing] no (by machine translation)

Comparative inhibition of tetrameric carbonyl reductase activity in pig heart cytosol by alkyl 4-pyridyl ketones

Context and objective: The present study is to elucidate the comparative inhibition of tetrameric carbonyl reductase (TCBR) activity by alkyl 4-pyridyl ketones, and to characterize its substrate-binding domain. Materials and methods: The inhibitory effect

The anion of 3-methyl-2-pyridin-4-yl-1,3-oxazine

n-Butyllithium at -78°C readily abstracts the methine proton from the title compound. The anion reacts efficiently with a range of electrophiles to provide 4-pyridyl ketones upon acid hydrolysis.