BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE

Base Information

Chemical Name:BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE
CAS No.:342816-00-6
Molecular Formula:C₇H₈F₂N₂O
Molecular Weight:174.15
Hs Code.:
Mol file:342816-00-6.mol

Synonyms:BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE

Suppliers and Price of BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE 95.00%
5MG
$ 499.28

Total 2 raw suppliers

Chemical Property of BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE

Chemical Property:

PSA：51.48000
LogP:1.86590

Purity/Quality:

99%+ ^*data from raw suppliers

BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE

There total 3 articles about BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 342815-99-0
2-(2-azido-1,1-difluoro-ethyl)-pyridine N-oxide

: 342816-00-6
2,2-difluoro-2-(1-oxido-2-pyridintl)ethylamine

Guidance literature:: 2-(2-azido-1,1-difluoro-ethyl)-pyridine N-oxide; With triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 1h;

With water; In tetrahydrofuran; at 20 - 55 ℃; for 14h;

Reference yield: 80.0%

: 435345-04-3
2,2-difluoro-2-(2-pyridyl)ethylamine benzenesulfonic acid salt

: 342816-00-6
2,2-difluoro-2-(1-oxido-2-pyridintl)ethylamine

Guidance literature:: With urea hydroperoxide; trifluoroacetic anhydride; In acetonitrile; at -5 ℃; for 0.5h;
DOI:10.1021/jo034835e

Reference yield:

: 267875-67-2
2,2-difluoro-2-(pyridin-2-yl)ethylazide

: 342816-00-6
2,2-difluoro-2-(1-oxido-2-pyridintl)ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: MCPBA / 1,2-dichloro-ethane / 55 °C

2: aq. PPh₃ / tetrahydrofuran

With 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; In tetrahydrofuran; 1,2-dichloro-ethane; 2: Staudinger reduction;
DOI:10.1016/S0960-894X(03)00099-4