17β-(Acetyloxy)-6β-fluoroestr-4-en-3-one

Base Information

Chemical Name:17β-(Acetyloxy)-6β-fluoroestr-4-en-3-one
CAS No.:18119-95-4
Molecular Formula:C20H27FO3
Molecular Weight:334.4249832
Hs Code.:
Mol file:18119-95-4.mol

Synonyms:Acetic acid (6R,8R,9S,10R,13S,14S,17S)-6-fluoro-13-methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester;

Suppliers and Price of 17β-(Acetyloxy)-6β-fluoroestr-4-en-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 17β-(Acetyloxy)-6β-fluoroestr-4-en-3-one

Chemical Property:

Melting Point:132 - 134 °C
PSA：43.37000
LogP:4.00790

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 17β-(Acetyloxy)-6β-fluoroestr-4-en-3-one

There total 3 articles about 17β-(Acetyloxy)-6β-fluoroestr-4-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4999-76-2
3,17β-diacetoxyoestra-3,5-diene

: 3801-28-3
17β-acetoxy-6α-fluoro-4-estren-3-one

: 18119-95-4
17β-acetoxy-6β-fluoro-4-estren-3-one

Guidance literature:: With 1-fluoropyridinium pyridine heptafluorodiborate; In acetonitrile; at 38 - 40 ℃; for 168h; Yield given. Yields of byproduct given;
DOI:10.1016/0039-128X(95)00009-F

Reference yield:

: 4999-76-2
3,17β-diacetoxyoestra-3,5-diene

: 18119-95-4
17β-acetoxy-6β-fluoro-4-estren-3-one

Guidance literature:: With hypofluorous acid trifluoromethyl ester; In chloroform; trichlorofluoromethane; at -70 ℃;

Reference yield:

: 434-22-0
19-nortestosterone

: 18119-95-4
17β-acetoxy-6β-fluoro-4-estren-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: Ac₂O

2: CF₃OF / CCl₃F; CHCl₃ / -70 °C

With hypofluorous acid trifluoromethyl ester; acetic anhydride; In chloroform; trichlorofluoromethane;