PF 04418948

Base Information

Chemical Name:PF 04418948
CAS No.:1078166-57-0
Molecular Formula:C22H21F3N6O3S
Molecular Weight:409.414
Hs Code.:
Mol file:1078166-57-0.mol

Synonyms:PF 04418948;1-(4-FLUOROBENZOYL)-3-[(6-METHOXYNAPHTHALEN-2-YL)OXYMETHYL]AZETIDINE-3-CARBOXYLIC ACID;1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid

Suppliers and Price of PF 04418948

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
PF04418948
25mg
$ 340.00

Tocris
PF04418948 ≥99%(HPLC)
50
$ 908.00

Tocris
PF04418948 ≥99%(HPLC)
10
$ 216.00

Sigma-Aldrich
PF-04418948 ≥98% (HPLC)
5mg
$ 99.20

Sigma-Aldrich
PF-04418948 ≥98% (HPLC)
25mg
$ 401.00

Medical Isotopes, Inc.
PF04418948
100 mg
$ 2200.00

Medical Isotopes, Inc.
PF04418948
10 mg
$ 675.00

ChemScene
PF-04418948 99.22%
50mg
$ 440.00

ChemScene
PF-04418948 99.22%
10mg
$ 110.00

ChemScene
PF-04418948 99.22%
5mg
$ 70.00

Total 21 raw suppliers

Chemical Property of PF 04418948

Chemical Property:

Appearance/Colour:White to off-white solid
Boiling Point:639.1±55.0 °C(Predicted)
PKA:3.25±0.20(Predicted)
PSA：76.07000
Density:1.357±0.06 g/cm3(Predicted)
LogP:3.53120
Storage Temp.:room temp
Solubility.:DMSO: soluble20mg/mL, clear

Purity/Quality:

99%, ^*data from raw suppliers

PF04418948 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses PF 04418948 acts as a novel, potent and selective prostoglandin EP2 receptor antagonist. PF-04418948 has been used in TG (trigeminal ganglion) explant culture.

Technology Process of PF 04418948

There total 1 articles about PF 04418948 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1078166-69-4
ethyl 1-(4-fluorobenzoyl)-3-{[(6-methoxy-2-naphthyl)oxy]methyl}azetidine-3-carboxylate

: 1078166-57-0
PF-04418948

Guidance literature:: ethyl 1-(4-fluorobenzoyl)-3-{[(6-methoxy-2-naphthyl)oxy]methyl}azetidine-3-carboxylate; With water; sodium trimethylsilanolate; In acetonitrile; at 20 ℃; for 4h;

With phosphoric acid; water; In acetonitrile; at 0 - 20 ℃; for 3h; Product distribution / selectivity;

Reference yield: 94.0%

: 1078166-57-0
PF-04418948

: 1078167-20-0
1-(4-Fluorobenzoyl)-3-{[(6-methoxy-2-naphthyl)oxy]methyl}azetidine-3-carbonitrile

Guidance literature:: With trimethylene hydrogen phosphate; ammonium chloride; triethylamine; In tetrahydrofuran; ethyl acetate; for 18h; Heating / reflux;