tert-Butyl-D9 4-Nitrophenyl Carbonate

Base Information

• Chemical Name: tert-Butyl-D9 4-Nitrophenyl Carbonate
• CAS No.: 1190006-35-9
• Molecular Formula: C11H4D9NO5
• Molecular Weight: 248.280076002
• Mol file: 1190006-35-9.mol

Synonyms:tert-Butyl-D9 4-Nitrophenyl Carbonate;1,1-Dimethylethyl 4-Nitrophenyl Ester Carbonic Acid;tert-Butyl p-Nitrophenyl Carbonat;tert-Butyl p-Nitrophenyl Ester Carbonic Acid

Chemical Property of tert-Butyl-D9 4-Nitrophenyl Carbonate

Chemical Property:

• Melting Point: 62-63°C
• PSA: 81.35000
• LogP: 3.43190
• Storage Temp.: -20?C Freezer
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl-d9 4-Nitrophenyl Carbonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tert-Butyl-D9 4-Nitrophenyl Carbonate

There total 1 articles about tert-Butyl-D9 4-Nitrophenyl Carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.9%

tert-butanol-d10 (53001-22-2) + 4-Nitrophenyl chloroformate (7693-46-1) → C11H4(2)H9NO5 (1190006-35-9)

Guidance literature:

With pyridine; for 4h; Inert atmosphere;

Reference yield:

C11H4(2)H9NO5 (1190006-35-9) → C46H54(2)H9NO15 (1269040-39-2)

Guidance literature:

Multi-step reaction with 5 steps

1.1: dmap / water; tetrahydrofuran / 20 °C

2.1: camphor-10-sulfonic acid / dichloromethane / 20 °C / Inert atmosphere

3.1: water / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

4.1: dmap; pivaloyl chloride; 4-methyl-morpholine / tetrahydrofuran / 3.5 h / 20 °C

5.1: hydrogenchloride; water / methanol / 3.5 h / 0 °C / pH 1.6

5.2: 0 °C

With 4-methyl-morpholine; hydrogenchloride; dmap; camphor-10-sulfonic acid; water; pivaloyl chloride; In tetrahydrofuran; methanol; dichloromethane; water;

Reference yield:

C11H4(2)H9NO5 (1190006-35-9) → C22H24(2)H9NO7 (1269040-51-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dmap / water; tetrahydrofuran / 20 °C

2: camphor-10-sulfonic acid / dichloromethane / 20 °C / Inert atmosphere

With dmap; camphor-10-sulfonic acid; In tetrahydrofuran; dichloromethane; water;

upstream raw materials:

tert-butanol-d10

4-Nitrophenyl chloroformate

Downstream raw materials:

C₄₆H₅₄⁽²⁾H₉NO₁₅

C₂₂H₂₄⁽²⁾H₉NO₇

C₂₁H₂₁⁽²⁾H₉NO₇^(1-)*Na⁽¹⁺⁾

C₅₅H₆₂⁽²⁾H₉NO₁₇

Refernces