(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol

Base Information

Chemical Name:(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol
CAS No.:243640-19-9
Molecular Formula:C14H21NO3
Molecular Weight:251.326
Hs Code.:
DSSTox Substance ID:DTXSID10431982
Nikkaji Number:J1.431.072J
Wikidata:Q82246039
Mol file:243640-19-9.mol

Synonyms:(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol;243640-19-9;(R)-(2,3-dimethoxyphenyl)-piperidin-4-ylmethanol;SCHEMBL3048141;DTXSID10431982;LZRHDSQWBVFQMC-CYBMUJFWSA-N;AKOS030242164;J-015464;(R)-alpha-(2,3-dimethoxyphenyl)-4-piperidinemethanol;(alphaR)-alpha-(4-Piperidinyl)-2,3-dimethoxybenzyl alcohol

Suppliers and Price of (R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol
25mg
$ 1320.00

TRC
(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol
2.5mg
$ 165.00

Medical Isotopes, Inc.
(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol
25 mg
$ 2200.00

Medical Isotopes, Inc.
(R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol
2.5 mg
$ 650.00

American Custom Chemicals Corporation
(R)-4-[1-HYDROXY-1-(2,3-DIMETHOXYPHENYL)METHYL]PIPERIDINE 95.00%
5MG
$ 505.93

Total 1 raw suppliers

Chemical Property of (R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol

Chemical Property:

Boiling Point:404.8±45.0 °C(Predicted)
PKA:13.93±0.20(Predicted)
PSA：50.72000
Density:1.106±0.06 g/cm3(Predicted)
LogP:2.06560
Solubility.:Chloroform, Dichloromethane, Methanol
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:251.15214353
Heavy Atom Count:18
Complexity:243

Purity/Quality:: (R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1OC)C(C2CCNCC2)O
Isomeric SMILES:COC1=CC=CC(=C1OC)[C@@H](C2CCNCC2)O

Technology Process of (R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol

There total 13 articles about (R)-(2,3-Dimethoxyphenyl)-4-piperidinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 140235-25-2
(+/-)-α-(2,3-dimethoxyphenyl)-4-piperidinemethanol

: 243640-19-9
(2,3‐dimethoxyphenyl)(piperidine‐4‐yl)methanol

Guidance literature:: With (2S,3S)-di-4-toluoyltartaric acid; In methanol; Heating;
DOI:10.1016/S0968-0896(00)00175-9

Reference yield: 34.0%

: 139290-71-4
4-(2,3-Dimethoxybenzoyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

: 243640-19-9
(2,3‐dimethoxyphenyl)(piperidine‐4‐yl)methanol

Guidance literature:: 4-(2,3-Dimethoxybenzoyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; With B-chlorodiisopinocampheylborane; In tetrahydrofuran; at -10 - 15 ℃; for 168h;

With hydrogenchloride; In water; at 15 ℃; for 0.0833333h; Product distribution / selectivity;

Reference yield:

: 869749-09-7
(R)-α-(2,3-dimethoxyphenyl)-4-piperidinemethanol, (2R,3R)-(-)-di-(p-toluoyl)tartaric acid salt

: 32634-66-5
Di-p-toluoyl-L-tartaric acid

: 243640-19-9
(2,3‐dimethoxyphenyl)(piperidine‐4‐yl)methanol

Guidance literature:: (R)-α-(2,3-dimethoxyphenyl)-4-piperidinemethanol, (2R,3R)-(-)-di-(p-toluoyl)tartaric acid salt; With ammonia; In methanol; water; for 2h;

With hydrogenchloride; In water; Product distribution / selectivity;