1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID

Base Information

• Chemical Name: 1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID
• CAS No.: 345297-65-6
• Molecular Formula: C11H10N2O5
• Molecular Weight: 250.21
• Mol file: 345297-65-6.mol

Synonyms:1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID;1-(3-NITRO-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID;5-keto-1-(3-nitrophenyl)pyrrolidine-3-carboxylic acid;Maybridge1_007948;Oprea1_257308

Chemical Property of 1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID

Chemical Property:

• PSA: 103.43000
• LogP: 1.62050

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-(3-Nitrophenyl)-5-oxopyrrolidine-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID

There total 1 articles about 1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-methylenesuccinic acid (97-65-4,25119-64-6) + 3-nitro-aniline (99-09-2) → 1-(3-nitro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid (345297-65-6)

Guidance literature:

at 110 ℃; for 8h;

DOI:10.1016/j.bmcl.2004.03.033

Reference yield: 90.0%

1-(3-nitro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid (345297-65-6) + 3-amino-3-pyridin-3-yl-propionic acid ethyl ester (62247-22-7) → ethyl 3-{(1-(3-nitrophenyl)-5-oxopyrrolidin-3-yl)carbonylamino}-3-(pyridin-3-yl)propanoate (345297-66-7)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 8h;

DOI:10.1016/j.bmcl.2004.03.033

Reference yield:

1-(3-nitro-phenyl)-5-oxo-pyrrolidine-3-carboxylic acid (345297-65-6) → methyl 1-(3-nitrophenyl)-5-oxopyrrolidine-3-carboxylate

Guidance literature:

With hydrogenchloride; sodium hydroxide; thionyl chloride; In methanol; dichloromethane; ethyl acetate;

upstream raw materials:

2-methylenesuccinic acid

3-nitro-aniline

Downstream raw materials:

ethyl 3-{(1-(3-nitrophenyl)-5-oxopyrrolidin-3-yl)carbonylamino}-3-(pyridin-3-yl)propanoate

ethyl 3-{(1-(3-aminophenyl)-5-oxopyrrolidin-3-yl)carbonylamino}-3-(pyridin-3-yl)-propanoate

(S)-4-benzyl-3-((R)-1-(3-nitrophenyl)-5-oxopyrrolidine-3-carbonyl)oxazolidin-2-one

(S)-4-benzyl-3-((S)-1-(3-nitrophenyl)-5-oxopyrrolidine-3-carbonyl)oxazolidin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 345297-65-6 1-(3-NITROPHENYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send