Technology Process of (S)-2-aMino-6-(3-(3-(3-Methyl-3H-diazirin-3-yl)propyl)ureido)hexanoic acid
There total 5 articles about (S)-2-aMino-6-(3-(3-(3-Methyl-3H-diazirin-3-yl)propyl)ureido)hexanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dichloromethane / 0 - 20 °C
2.1: acetonitrile / 50 °C
3.1: lithium hydroxide; methanol; water / 4 h / 20 °C
3.2: 1 h / Reflux
With
methanol; water; lithium hydroxide;
In
dichloromethane; acetonitrile;
- Guidance literature:
-
C18H33N5O5;
With
methanol; water; lithium hydroxide;
at 20 ℃;
for 4h;
With
hydrogenchloride;
for 1h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: ammonia / 5 h / -40 °C
1.2: -60 - 20 °C
2.1: pyridine / 0 °C
3.1: sodium azide / N,N-dimethyl-formamide / 20 °C
3.2: 20 °C
4.1: acetonitrile / 50 °C
5.1: lithium hydroxide; methanol; water / 4 h / 20 °C
5.2: 1 h / Reflux
With
pyridine; methanol; sodium azide; ammonia; water; lithium hydroxide;
In
N,N-dimethyl-formamide; acetonitrile;