SB-423562

Base Information

• Chemical Name: SB-423562
• CAS No.: 351490-27-2
• Molecular Formula: C₂₆H₃₂N₂O₄
• Molecular Weight: 436.551
• UNII: 615K7YBS59
• Wikidata: Q27896275
• Pharos Ligand ID: 7LX1S8SHWS7C
• ChEMBL ID: CHEMBL1084513
• Mol file: 351490-27-2.mol

Synonyms:SB 423562;SB-423562;SB423562

Chemical Property of SB-423562

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 436.23620751
• Heavy Atom Count: 32
• Complexity: 644

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(CC1CC2=CC=CC=C2C1)NCC(COC3=C(C=CC(=C3)CCC(=O)O)C#N)O
• Isomeric SMILES: CC(C)(CC1CC2=CC=CC=C2C1)NC[C@H](COC3=C(C=CC(=C3)CCC(=O)O)C#N)O
• Recent ClinicalTrials: A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations

Technology Process of SB-423562

There total 2 articles about SB-423562 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

SB-423557 (351490-26-1) → SB-423562 (351490-27-2)

Guidance literature:

With sodium hydroxide; In ethanol; water;

Reference yield:

→ SB-423562 (351490-27-2)

Guidance literature:

Reference yield: 80.0%

SB-423562 (351490-27-2) + benzyl bromide (100-39-0) → C33H38N2O4 (863016-10-8)

Guidance literature:

SB-423562; With caesium carbonate; In ethanol; water; pH=8;

benzyl bromide; In DMF (N,N-dimethyl-formamide); at 60 ℃; Product distribution / selectivity;

upstream raw materials:

SB-423557

Downstream raw materials:

C₃₃H₃₈N₂O₄