(S)-1-(4-ethylphenyl)ethanol

Base Information

• Chemical Name: (S)-1-(4-ethylphenyl)ethanol
• CAS No.: 101219-72-1
• Molecular Formula: C10H14O
• Molecular Weight: 150.221
• Mol file: 101219-72-1.mol

Synonyms:(S)-1-(4-ethylphenyl)ethanol

Chemical Property of (S)-1-(4-ethylphenyl)ethanol

Chemical Property:

• Boiling Point: 117 - 118 °C (13 mmHg)
• PSA: 20.23000
• LogP: 2.30230

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-1-(4-ethylphenyl)ethanol

There total 8 articles about (S)-1-(4-ethylphenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-ethylacetophenone (937-30-4) → (S)-1-(4-ethylphenyl)ethan-1-ol (101219-72-1)

Guidance literature:

With triiron dodecarbonyl; C₅₂H₅₈N₄P₂; hydrogen; potassium hydroxide; In methanol; at 45 ℃; for 10h; under 37503.8 Torr; enantioselective reaction;

DOI:10.1021/ja5003636

Reference yield:

1,4-diethylbenzene (105-05-5) → (S)-1-(4-ethylphenyl)ethan-1-ol (101219-72-1)

Guidance literature:

With hydrogenchloride; ferrocenium(III) tetrafluoroborate; ethylbenzene dehydrogenase; In water; tert-butyl alcohol; at 30 ℃; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.jinorgbio.2014.05.006

Reference yield:

1-(α-acetoxyethyl)-4-ethylbenzene (103966-60-5) → (S)-1-(4-ethylphenyl)ethan-1-ol (101219-72-1) + 1-(R)-(4'-ethylphenyl)ethanol (54225-75-1)

Guidance literature:

With carboxyl esterase; In aq. buffer; at 50 ℃; pH=8; enantioselective reaction; Enzymatic reaction;

DOI:10.1016/j.bioorg.2020.104214

upstream raw materials:

1-(4-ethylphenyl)ethanol

(-)-(S)-N,N-dimethyl-1-phenylethylamine

acetic anhydride

4-ethylacetophenone

Downstream raw materials:

(S,S)-α,α'-dimethyl-1,4-benzenedimethanol