2-Methoxy-4-methyl-5-pyrimidinamine

Base Information

• Chemical Name: 2-Methoxy-4-methyl-5-pyrimidinamine
• CAS No.: 908099-97-8
• Molecular Formula: C₆H₉N₃O
• Molecular Weight: 139.157
• Mol file: 908099-97-8.mol

Synonyms:2-Methoxy-4-methyl-5-pyrimidinamine;2-Methoxy-4-MethylpyriMidin-5-aMine;2-Methoxy-4-methyl-pyrimidin-5-ylamine

Chemical Property of 2-Methoxy-4-methyl-5-pyrimidinamine

Chemical Property:

• Boiling Point: 300.4±34.0 °C(Predicted)
• PKA: 2.98±0.29(Predicted)
• PSA: 61.03000
• Density: 1.174±0.06 g/cm3(Predicted)
• LogP: 0.95700
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

2-Methoxy-4-methyl-pyrimidin-5-ylamine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methoxy-4-methyl-5-pyrimidinamine

There total 3 articles about 2-Methoxy-4-methyl-5-pyrimidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4-chloro-2-methoxy-6-methyl-5-nitropyrimidine (84538-47-6) → 2-methoxy-4-methylpyrimidin-5-amine (908099-97-8)

Guidance literature:

With hydrogen; triethylamine; In methanol; at 50 ℃; for 5h; under 22502.3 Torr; Temperature; Solvent; Autoclave;

Reference yield:

2-chloro-4-methyl-5-aminopyrimidine (20090-69-1) + sodium methylate (124-41-4) → 2-methoxy-4-methylpyrimidin-5-amine (908099-97-8)

Guidance literature:

at 100 ℃;

Reference yield:

→ 2-methoxy-4-methylpyrimidin-5-amine (908099-97-8)

Guidance literature:

With copper; In methanol; at 150 ℃; for 24h; Sealed tube;

upstream raw materials:

2-chloro-4-methyl-5-aminopyrimidine

sodium methylate

4-chloro-2-methoxy-6-methyl-5-nitropyrimidine