3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid

Base Information

Chemical Name:3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid
CAS No.:372144-22-4
Molecular Formula:C₁₃H₁₈N₂O₄
Molecular Weight:266.297
Hs Code.:
Mol file:372144-22-4.mol

Synonyms:3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid;3-(2-PYRIDYL)-3-(BOC-AMINO)PROPIONIC ACID

Suppliers and Price of 3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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American Custom Chemicals Corporation
3-[(TERT-BUTOXYCARBONYL)AMINO]-3-PYRIDIN-2-YLPROPANOIC ACID 95.00%
5MG
$ 505.48

Total 1 raw suppliers

Chemical Property of 3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid

Chemical Property:

Purity/Quality:: 3-[(TERT-BUTOXYCARBONYL)AMINO]-3-PYRIDIN-2-YLPROPANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid

There total 5 articles about 3-[(tert-butoxycarbonyl)amino]-3-pyridin-2-ylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 3-((tert-butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoate

: 372144-22-4
3-((tert-butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃;

Reference yield:

: 872-85-5
pyridine-4-carbaldehyde

: 372144-22-4
3-((tert-butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: titanium(IV) tetraethanolate / tetrahydrofuran / 80 °C

2.1: lithium diisopropyl amide / tetrahydrofuran; tert-butyl methyl ether / 1.5 h / -78 °C / Inert atmosphere

2.2: 3.5 h / -78 °C

3.1: hydrogenchloride / 1,4-dioxane / 8 h / 0 - 20 °C

4.1: sodium hydrogencarbonate / 1,4-dioxane / 16 h / 20 °C

5.1: lithium hydroxide; water / methanol; tetrahydrofuran / 20 °C

With hydrogenchloride; titanium(IV) tetraethanolate; water; sodium hydrogencarbonate; lithium hydroxide; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; methanol; tert-butyl methyl ether;

Reference yield:

: 2-methyl-N-[(pyridin-4-yl)methylidene]propane-2-sulfinamide

: 372144-22-4
3-((tert-butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; tert-butyl methyl ether / 1.5 h / -78 °C / Inert atmosphere

1.2: 3.5 h / -78 °C

2.1: hydrogenchloride / 1,4-dioxane / 8 h / 0 - 20 °C

3.1: sodium hydrogencarbonate / 1,4-dioxane / 16 h / 20 °C

4.1: lithium hydroxide; water / methanol; tetrahydrofuran / 20 °C

With hydrogenchloride; water; sodium hydrogencarbonate; lithium hydroxide; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; methanol; tert-butyl methyl ether;