3-amino-3-pyridin-4-yl-propionic acid ethyl ester

Base Information

• Chemical Name: 3-amino-3-pyridin-4-yl-propionic acid ethyl ester
• CAS No.: 77742-28-0
• Molecular Formula: C10H14N2O2
• Molecular Weight: 194.23
• Hs Code.: 2933399090
• Mol file: 77742-28-0.mol

Synonyms:4-Pyridinepropanoic acid, β-amino-, ethyl ester;3-amino-3-pyridin-4-yl-propionic acid ethyl ester

Chemical Property of 3-amino-3-pyridin-4-yl-propionic acid ethyl ester

Chemical Property:

• PSA: 65.21000
• LogP: 1.73490
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

ethyl3-amino-3-(pyridin-4-yl)propanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-amino-3-pyridin-4-yl-propionic acid ethyl ester

There total 6 articles about 3-amino-3-pyridin-4-yl-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C10H12N2O2 → (±)-ethyl 3-amino-3-(pyridin-4-yl)propanoate (77742-28-0)

Guidance literature:

With 1% Pd on activated carbon; hydrogen; In ethanol; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1021/acs.inorgchem.5b02650

Reference yield: 74.0%

ethyl 3-amino-3-(4-pyridyl)propenoate (70076-13-0) → (±)-ethyl 3-amino-3-(pyridin-4-yl)propanoate (77742-28-0)

Guidance literature:

ethyl 3-amino-3-(4-pyridyl)propenoate; With Pearlman catalyst; hydrogen; acetic acid; In ethanol; at 20 ℃; for 24h; under 760.051 Torr;

With potassium carbonate; In water;

DOI:10.1016/j.tetasy.2009.06.019

Reference yield:

ethyl 3-((tert-butylsulfinyl)amino)-3-(pyridin-4-yl)propanoate → (±)-ethyl 3-amino-3-(pyridin-4-yl)propanoate (77742-28-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 0 - 20 ℃; for 8h;

upstream raw materials:

ethyl 3-amino-3-(4-pyridyl)propenoate

pyridine-4-carbonitrile

pyridine-4-carbaldehyde

Downstream raw materials:

3-((tert-butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid

(S)-3-amino-3-(4-pyridyl)propanoic acid

ethyl (R)-3-amino-3-(4-pyridyl)propanoate