6,8-Dimethylquinoline-3-carboxylic acid

Base Information

Chemical Name:6,8-Dimethylquinoline-3-carboxylic acid
CAS No.:213013-16-2
Molecular Formula:C₁₂H₁₁NO₂
Molecular Weight:201.225
Hs Code.:2933499090
DSSTox Substance ID:DTXSID40589127
Wikidata:Q82482290
Mol file:213013-16-2.mol

Synonyms:6,8-Dimethylquinoline-3-carboxylic acid;213013-16-2;6,8-Dimethylquinoline-3-carboxylicacid;SCHEMBL26580385;DTXSID40589127;AMY17652;MFCD09787810;AKOS016845653;AB52292;AS-63924;DB-066478;CS-0449887;D93288

Suppliers and Price of 6,8-Dimethylquinoline-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6,8-Dimethylquinoline-3-carboxylicacid 95+%
1g
$ 510.00

Chemenu
6,8-dimethylquinoline-3-carboxylicacid 95%
1g
$ 482.00

American Custom Chemicals Corporation
6,8-DIMETHYLQUINOLINE-3-CARBOXYLIC ACID 95.00%
5MG
$ 501.91

Alichem
6,8-Dimethylquinoline-3-carboxylicacid
1g
$ 449.28

Total 7 raw suppliers

Chemical Property of 6,8-Dimethylquinoline-3-carboxylic acid

Chemical Property:

Vapor Pressure:2.75E-06mmHg at 25°C
Boiling Point:374.9°C at 760 mmHg
Flash Point:180.5°C
PSA：50.19000
Density:1.243g/cm³
LogP:2.54980
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:201.078978594
Heavy Atom Count:15
Complexity:254

Purity/Quality:

98%min ^*data from raw suppliers

6,8-Dimethylquinoline-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C(=C1)C=C(C=N2)C(=O)O)C

Technology Process of 6,8-Dimethylquinoline-3-carboxylic acid

There total 6 articles about 6,8-Dimethylquinoline-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(2,4,6-trimethyl-phenyl)-acetimidic acid methyl ester

: 213013-16-2
6,8-dimethyl-quinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / triethylamine / diethyl ether / 4 h / 0 °C

2: 23 percent / 3 h / 450 °C

3: 84 percent / 700 °C

4: 20 mg / aq. KOH / 0.5 h / 80 °C

With potassium hydroxide; triethylamine; In diethyl ether; 1: Cyclization / 2: Ring cleavage / 3: Cyclization / 4: Hydrolysis;
DOI:10.1021/jo9722562

Reference yield:

: 213013-11-7
6,8-dimethyl-quinoline-3-carboxylic acid methyl ester

: 213013-16-2
6,8-dimethyl-quinoline-3-carboxylic acid

Guidance literature:: With potassium hydroxide; at 80 ℃; for 0.5h;
DOI:10.1021/jo9722562

Reference yield:

: 213013-09-3
5-methoxy-1-(2,4,6-trimethylphenyl)pyrrole-2,3-dione

: 213013-16-2
6,8-dimethyl-quinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 23 percent / 3 h / 450 °C

2: 84 percent / 700 °C

3: 20 mg / aq. KOH / 0.5 h / 80 °C

With potassium hydroxide; 1: Ring cleavage / 2: Cyclization / 3: Hydrolysis;
DOI:10.1021/jo9722562