(4-Chlorophenyl)(indolin-1-yl)methanone

Base Information

Chemical Name:(4-Chlorophenyl)(indolin-1-yl)methanone
CAS No.:211576-30-6
Molecular Formula:C15H12ClNO
Molecular Weight:257.719
Hs Code.:2933990090
DSSTox Substance ID:DTXSID901324012
ChEMBL ID:CHEMBL1516956
Mol file:211576-30-6.mol

Synonyms:(4-Chlorophenyl)(indolin-1-yl)methanone;211576-30-6;(4-chlorophenyl)-(2,3-dihydroindol-1-yl)methanone;1-(4-chlorobenzoyl)indoline;MLS001209665;(4-Chloro-phenyl)-(2,3-dihydro-indol-1-yl)-methanone;CHEMBL1516956;DTXSID901324012;HMS2822B14;STK087484;AKOS000604597;SMR000513573;CS-0333636;1-(4-chlorobenzoyl)-2,3-dihydro-1H-indole;Z30624412;(4-chlorophenyl)(2,3-dihydro-1H-indol-1-yl)methanone

Suppliers and Price of (4-Chlorophenyl)(indolin-1-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(4-Chlorophenyl)(indolin-1-yl)methanone 95+%
5g
$ 339.00

Chemenu
(4-chlorophenyl)(indolin-1-yl)methanone 95%
5g
$ 320.00

Alichem
(4-Chlorophenyl)(indolin-1-yl)methanone
5g
$ 270.48

Total 3 raw suppliers

Chemical Property of (4-Chlorophenyl)(indolin-1-yl)methanone

Chemical Property:

PSA：20.31000
LogP:3.60790
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:257.0607417
Heavy Atom Count:18
Complexity:312

Purity/Quality:

99% ^*data from raw suppliers

(4-Chlorophenyl)(indolin-1-yl)methanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C2=CC=CC=C21)C(=O)C3=CC=C(C=C3)Cl

Technology Process of (4-Chlorophenyl)(indolin-1-yl)methanone

There total 4 articles about (4-Chlorophenyl)(indolin-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1297604-82-0
2-(triphenylphosphoranylideneamino)phenethyl 4-chlorobenzoate

: 211576-30-6
(4-chlorophenyl)(indolin-1-yl)methanone

Guidance literature:: In 5,5-dimethyl-1,3-cyclohexadiene; at 138 ℃; for 3h; Inert atmosphere;
DOI:10.1055/s-0030-1259280

Reference yield: 71.0%

: 496-15-1
1-indoline

: 122-01-0
4-chloro-benzoyl chloride

: 211576-30-6
(4-chlorophenyl)(indolin-1-yl)methanone

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/jacs.8b03739

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 211576-30-6
(4-chlorophenyl)(indolin-1-yl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 0.5 h / 20 °C

2: dichloromethane / 1 h

3: 5,5-dimethyl-1,3-cyclohexadiene / 3 h / 138 °C / Inert atmosphere

With triethylamine; In 5,5-dimethyl-1,3-cyclohexadiene; dichloromethane; 2: Staudinger reaction;
DOI:10.1055/s-0030-1259280