2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine

Base Information

• Chemical Name: 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine
• CAS No.: 77989-14-1
• Molecular Formula: C21H14ClN3
• Molecular Weight: 343.815
• Mol file: 77989-14-1.mol

Synonyms:2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine

Chemical Property of 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine

Chemical Property:

• Melting Point: 135 - 136 °C
• PSA: 38.67000
• LogP: 5.52600

Purity/Quality:

95%, 99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine

There total 6 articles about 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-Chlorobenzyl alcohol (17849-38-6) + benzamidine monohydrochloride (1670-14-0) → 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine (77989-14-1)

Guidance literature:

With oxygen; copper(II) acetate monohydrate; sodium carbonate; In toluene; at 110 ℃; for 24h;

DOI:10.1039/c5ob00724k

Reference yield: 79.0%

2'-chloro-benzeneacetic acid (2444-36-2) + benzamidine monohydrochloride (1670-14-0) → 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine (77989-14-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃;

DOI:10.1002/ejoc.201800178

Reference yield: 77.0%

benzamidine monohydrochloride (1670-14-0) + 2-chloro-benzaldehyde (89-98-5) → 2-(2-chlorophenyl)-4,6-diphenyl-1,3,5-triazine (77989-14-1)

Guidance literature:

With copper(II) acetate monohydrate; sodium carbonate; In toluene; at 100 ℃; for 24h;

DOI:10.1007/s10895-018-2235-2

upstream raw materials:

1-(2-chlorophenyl)-2-phenyl-1-ethanone

2-Chlorobenzyl alcohol

benzamidine monohydrochloride

2-methylchlorobenzene

Refernces

• 1、 Wang, Xueding,Xu, Yilian,Yang, Lu,Lu, Xiang,Zou, Hao,Yang, Weiqing,Zhang, Yuanyuan,Li, Zicheng,Ma, Menglin. "Synthesis, Spectra, and Theoretical Investigations of 1,3,5-Triazines Compounds as Ultraviolet Rays Absorber Based on Time-Dependent Density Functional Calculations and three-Dimensional Quantitative Structure-Property Relationship". . p. 707 - 723. Retrieved 2018/05/05.
• 2、 You, Qing,Wang, Fei,Wu, Chaoting,Shi, Tianchao,Min, Dewen,Chen, Huajun,Zhang, Wu. "Synthesis of 1,3,5-triazines via Cu(OAc)2-catalyzed aerobic oxidative coupling of alcohols and amidine hydrochlorides". supporting information. p. 6723 - 6727. Retrieved 2015/06/25.