(1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

Base Information

Chemical Name:(1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
CAS No.:1210344-30-1
Molecular Formula:C22H25ClO7
Molecular Weight:718.844
Hs Code.:
Mol file:1210344-30-1.mol

Synonyms:(1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(3R,4S,5S)-3,4,5-tris(benzyloxy)-6,6-bis(((4-methoxybenzyl)oxy)methyl)tetrahydro-2H-pyran-2-one

Suppliers and Price of (1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 14 raw suppliers

Chemical Property of (1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Useful:

Technology Process of (1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

There total 5 articles about (1R,2S,3S,4R,5R)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: (3R,4S,5S)-3,4,5-tris-benzyloxy-6,6-bis-(4-methoxybenzyloxymethyl)tetrahydropyran-2-ol

: 1210344-30-1
(3R,4S,5S)-3,4,5-tris-benzyloxy-6,6-bis-(4-methoxybenzyloxymethyl)tetrahydropyran-2-one

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 0 ℃;

Reference yield:

: C₃₀H₃₂O₆

: 1210344-30-1
(3R,4S,5S)-3,4,5-tris-benzyloxy-6,6-bis-(4-methoxybenzyloxymethyl)tetrahydropyran-2-one

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / water; isopropyl alcohol / 23 °C / Inert atmosphere

2: sodium hydride / N,N-dimethyl-formamide / 0 - 60 °C / Inert atmosphere

3: palladium dichloride / methanol; dichloromethane / 23 °C / Inert atmosphere

4: Inert atmosphere

With sodium hydride; sodium hydroxide; palladium dichloride; In methanol; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol; 1: Aldol condensation / 4: Swern oxidation;
DOI:10.1021/jm200049r

Reference yield:

: 1210344-28-7
(3S,4S,5R)-6-allyloxy-3,4,5-tris-benzyloxy-2,2-bis(4-methoxybenzyloxymethyl)tetrahydropyrane

: 1210344-30-1
(3R,4S,5S)-3,4,5-tris-benzyloxy-6,6-bis-(4-methoxybenzyloxymethyl)tetrahydropyran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: palladium dichloride / methanol; dichloromethane / 23 °C / Inert atmosphere

2: Inert atmosphere

With palladium dichloride; In methanol; dichloromethane; 2: Swern oxidation;
DOI:10.1021/jm200049r