2-ethynylbenzaMide

Base Information

Chemical Name:2-ethynylbenzaMide
CAS No.:1207252-50-3
Molecular Formula:C9H7NO
Molecular Weight:145.161
Hs Code.:
Mol file:1207252-50-3.mol

Synonyms:2-ethynylbenzaMide

Suppliers and Price of 2-ethynylbenzaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-ethynylbenzaMide

Chemical Property:

Purity/Quality:: 98%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-ethynylbenzaMide

There total 2 articles about 2-ethynylbenzaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4001-73-4
2-Bromobenzamide

: 1207252-50-3
2-ethynylbenzylamide

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine / 90 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C / Inert atmosphere

With copper(l) iodide; tetrabutyl ammonium fluoride; palladium diacetate; triethylamine; triphenylphosphine; In tetrahydrofuran; 1: Sonogashira coupling;
DOI:10.1002/adsc.201100095

Reference yield:

: 3930-83-4
o-iodobenzamide

: 1207252-50-3
2-ethynylbenzylamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / N,N-dimethyl-formamide / 0.08 h / 20 °C / Inert atmosphere

1.2: 2 h / 70 °C / Inert atmosphere

2.1: potassium fluoride dihydrate / methanol / 0.5 h / 25 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium fluoride dihydrate; In methanol; N,N-dimethyl-formamide; 1.1: |Sonogashira Cross-Coupling / 1.2: |Sonogashira Cross-Coupling;
DOI:10.1021/acs.joc.7b02903

Reference yield: 81.0%

: 1207252-50-3
2-ethynylbenzylamide

: 619-44-3
methyl 4-iodobenzoate

: 1425605-52-2
methyl 4-((2-carbamoylphenyl)ethynyl)benzoate

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 6h; Inert atmosphere;
DOI:10.1021/jo302794z