3930-83-4

Basic information

• Product Name: 2-IODOBENZAMIDE
• Synonyms: 2-IODOBENZAMIDE;2-iodo-benzamid;o-iodo-benzamid;NSC 136970;o-Iodobenzamide
• CAS NO: 3930-83-4
• Molecular Formula: C₇H₆INO
• Molecular Weight: 247.03
• Product Categories: Anilines, Amides & Amines;Iodine Compounds
• Mol File: 3930-83-4.mol
• Article Data: 31

Chemical Properties

• Melting Point: 184 °C
• Boiling Point: 322.518 °C at 760mmHg
• Flash Point: 148.854 °C
• Appearance: /
• Density: 1.897 g/cm³
• Vapor Pressure: 0.000278mmHg at 25°C
• Refractive Index: 1.66
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 15.46±0.50(Predicted)
• CAS DataBase Reference: 2-IODOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODOBENZAMIDE(3930-83-4)
• EPA Substance Registry System: 2-IODOBENZAMIDE(3930-83-4)

Safety Data

• RTECS: CV5399625
• Hazardous Substances Data: 3930-83-4(Hazardous Substances Data)

Usage

General Description

2-Iodobenzamide is a chemical compound with the molecular formula C7H6IN2O. It is a white to light brown solid that is used in organic synthesis and pharmaceutical research. 2-Iodobenzamide is a substituted benzamide derivative, and it is often utilized as a precursor in the preparation of various other organic compounds. This chemical is known to exhibit moderate toxicity and should be handled and stored with care. It is also important to follow proper safety protocols when working with 2-Iodobenzamide to minimize the risk of exposure and potential harm.

InChI:InChI=1/C7H6INO/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,(H2,9,10)

Upstream product

• 18282-40-1 1-ethyl-2-iodobenzene 
• 4001-73-4 2-Bromobenzamide 
• 26260-02-6 2-iodobenzaldehyde 
• 5159-41-1 2-iodobenzyl alcohol 
• 55-21-0 benzamide 
• 4387-36-4 2-iodobenzonitrile 
• 1885-29-6 anthranilic acid nitrile 
• 459-46-1 4-Fluorobenzyl bromide 
• 127-65-1 chloramine-T 
• 118-92-3 anthranilic acid 
• 88-67-5 2-Iodobenzoic acid 
• 57-13-6 urea 
• 609-67-6 2-Iodobenzoyl chloride 

Downstream Products

• 5152-34-1 2-dichloroiodanyl-benzoic acid amide 
• 13670-91-2 3-(4-methoxyphenyl)-2H-isoquinolin-1-one 
• 25407-08-3 2-((4-methoxyphenyl)ethynyl)benzamide 
• 25407-16-3 2-(naphthalen-1-ylethynyl)benzamide 
• 25410-95-1 3-Amino-2-(2-nitro-phenyl)-inden-1-on 
• 914379-14-9 3-(pyridin-3-yl)isoquinolin-1(2H)-one 
• 1133467-89-6 [N-(trifluoromethanesulfonyl)imino](2-carbamoylphenyl)-λ3-iodane 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 1022-45-3 2-phenyl-4(3H)-quinazolinone 
• 119-61-9 benzophenone 
• 18818-41-2 2-(4-methylphenyl)-4(3H)-quinazolinone 
• 1152-07-4 2-(4-methoxyphenyl)-3H-quinazolin-4-one 
• 7455-77-8 2-(4-chlorophenyl)-4(3H)-quinazolinone 
• 2634-33-5 1,2-benzisothiazolin-3-one 

Relevant articles and documents

A “universal” catalyst for aerobic oxidations to synthesize (hetero)aromatic aldehydes, ketones, esters, acids, nitriles, and amides

Functionalized (hetero)aromatic compounds are indispensable chemicals widely used in basic and applied sciences. Among these, especially aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides represent valuable fine and bulk chemicals, which are used in chemical, pharmaceutical, agrochemical, and material industries. For their synthesis, catalytic aerobic oxidation of alcohols constitutes a green, sustainable, and cost-effective process, which should ideally make use of active and selective 3D metals. Here, we report the preparation of graphitic layers encapsulated in Co-nanoparticles by pyrolysis of cobalt-piperazine-tartaric acid complex on carbon as a most general oxidation catalyst. This unique material allows for the synthesis of simple, functionalized, and structurally diverse (hetero)aromatic aldehydes, ketones, carboxylic acids, esters, nitriles, and amides from alcohols in excellent yields in the presence of air.

Ring Opening/Site Selective Cleavage in N-Acyl Glutarimide to Synthesize Primary Amides

A LiOH-promoted hydrolysis selective C-N cleavage of twisted N-acyl glutarimide for the synthesis of primary amides under mild conditions has been developed. The reaction is triggered by a ring opening of glutarimide followed by C-N cleavage to afford primary amides using 2 equiv of LiOH as the base at room temperature. The efficacy of the reactions was considered and administrated for various aryl and alkyl substituents in good yield with high selectivity. Moreover, gram-scale synthesis of primary amides using a continuous flow method was achieved. It is noted that our new methodology can apply under both batch and flow conditions for synthetic and industrial applications.

Transamidation for the Synthesis of Primary Amides at Room Temperature

Various primary amides have been synthesized using the transamidation of various tertiary amides under metal-free and mild reaction conditions. When (NH4)2CO3 reacts with a tertiary amide bearing an N-electron-withdrawing substituent, such as sulfonyl and diacyl, in DMSO at 25 °C, the desired primary amide product is formed in good yield with good funcctional group tolerance. In addition, N-tosylated lactam derivatives afforded their corresponding N-tosylamido alkyl amide products via a ring opening reaction.