()-thiazolidine-4-carboxylic acid

Base Information

Chemical Name:()-thiazolidine-4-carboxylic acid
CAS No.:19291-02-2
Molecular Formula:C₄H₇NO₂S
Molecular Weight:133.171
Hs Code.:

Synonyms:4-Thiazolidinecarboxylic acid, D-; L-4-Thiazolidinecarboxylic acid; thiobiline; 1,3-thiazolidine-4-carboxylic acid

Suppliers and Price of ()-thiazolidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 6 raw suppliers

Chemical Property of ()-thiazolidine-4-carboxylic acid

Chemical Property:

Vapor Pressure:7.63E-06mmHg at 25°C
Boiling Point:350.3°C at 760 mmHg
Flash Point:165.7°C
PSA：74.63000
Density:1.38g/cm³
LogP:0.06230

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

General Description ()-Thiazolidine-4-carboxylic acid (THC) is a racemic compound that can be resolved into its enantiomers, D- and L-THC, through asymmetric transformation or preferential crystallization methods. These enantiomers serve as intermediates for producing optically pure (R)- and (S)-cysteine, with yields ranging from 64% to 80% depending on the resolving agent (e.g., tartaric acid) and additives like salicylaldehyde. Preferential crystallization in aqueous or glycine solutions further enables efficient resolution, yielding D- and L-THC with high optical purity (93–100%), which can be hydrolyzed to enantiopure cysteine. L-amino acids such as L-isoleucine or L-cysteine can influence the preferential crystallization of specific THC enantiomers.

Technology Process of ()-thiazolidine-4-carboxylic acid

There total 15 articles about ()-thiazolidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%