4-CHROMANONE

Base Information

• Chemical Name: 4-CHROMANONE
• CAS No.: 1341-36-2
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 148.161
• Mol file: 1341-36-2.mol

Synonyms:CHROMAN-4-ONE;CHROMANONE;CHROMANONE, 4-;2,3-DIHYDRO-4H-CHROMEN-4-ONE;2,4-DIHYDRO-1-BENZOPYRAN-4-ONE;4-CHROMANONE 97%

Chemical Property of 4-CHROMANONE

Chemical Property:

• Vapor Pressure: 0.00624mmHg at 25°C
• Melting Point: 35-38 °C(lit.)
• Refractive Index: n20/D 1.575(lit.)
• Boiling Point: 127-128 °C13 mm Hg(lit.)
• Flash Point: >230 °F
• PSA: 26.30000
• Density: 1.196g/cm³
• LogP: 1.65180
• Water Solubility.: insoluble

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xn:Harmful
• Statements: R22:; R36/37/38:
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHROMANONE

There total 12 articles about 4-CHROMANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

palladium-on-activated carbon + Pd-on-carbon Powder + methyl 3-(2-oxocyclohexyl)propionate (10407-33-7,58769-44-1) → coumarin (91-64-5) + C6H4(CH2CH2C(O)O) (119-84-6,1341-36-2)

Guidance literature:

In methyl 3-(2-oxcyclohexyl)propionate;

Reference yield: 99.9%

→ coumarin (91-64-5) + C6H4(CH2CH2C(O)O) (119-84-6,1341-36-2)

Guidance literature:

Reference yield: 91.0%

7-(1-Phenyl-1H-tetrazol-5-yloxy)-chromen-2-one (77924-22-2) → 5-hydroxy-1-phenyltetrazole (5097-82-5) + coumarin (91-64-5) + C6H4(CH2CH2C(O)O) (119-84-6,1341-36-2)

Guidance literature:

With sodium hypophosphite; palladium on activated charcoal; In ethanol; water; benzene; for 0.916667h; Heating;

DOI:10.1016/0040-4020(82)80091-4

upstream raw materials:

β-phenylpropionyl peroxide

lead(IV) tetraacetate

dihydrocoumarin trimethylsilyl ketene acetal

7-(1-Phenyl-1H-tetrazol-5-yloxy)-chromen-2-one

Downstream raw materials:

3-ethyl-1-(2-hydroxyphenyl)-3-pentanol

6-bromo-2H-chromen-2-one

4-hydroxy-2,3-dihydroindan-1-one

6-bromo-3,4-dihydro-2H-1-benzopyran-2-one