DIEXO-3-AMINO-BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: DIEXO-3-AMINO-BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE
• CAS No.: 947601-81-2
• Molecular Formula: C₈H₁₁NO₂*ClH
• Molecular Weight: 189.642
• Hs Code.: 2922499990
• Mol file: 947601-81-2.mol

Synonyms:DIEXO-3-AMINO-BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE

Chemical Property of DIEXO-3-AMINO-BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE

Chemical Property:

• PSA: 63.32000
• LogP: 1.72270

Purity/Quality:

98%min ^*data from raw suppliers

exo-cis-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid hydrochloride ≥97.0% (AT) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIEXO-3-AMINO-BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE

There total 2 articles about DIEXO-3-AMINO-BICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(1R,2R,5S,6S)-3-azatricyclo[4.2.1.02,5]non-7-en-4-one (924272-78-6,670221-11-1) → (1S,2S,3R,4R)-3-Amino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; hydrochloride (947601-81-2,677757-33-4,677757-34-5)

Guidance literature:

With hydrogenchloride; In water; for 3h; Heating;

DOI:10.1016/j.tetasy.2003.12.034

Reference yield:

diexo-3-Aza-4-oxotricyclo<4.2.1.02,5>non-7-ene (14735-70-7,14805-31-3,924272-78-6,670221-11-1) → (1S,2S,3R,4R)-3-Amino-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; hydrochloride (947601-81-2,677757-33-4,677757-34-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 47 percent / Lipolase; water / diisopropyl ether / 192 h / 70 °C

2: 84 percent / HCl / H₂O / 3 h / Heating

With hydrogenchloride; lipolase; water; In di-isopropyl ether; water;

DOI:10.1016/j.tetasy.2003.12.034

upstream raw materials:

(1R,2R,5S,6S)-3-azatricyclo[4.2.1.0^2,5]non-7-en-4-one

diexo-3-Aza-4-oxotricyclo<4.2.1.0^2,5>non-7-ene

Refernces