GLYCINE-2-13C ETHYL ESTER, HYDROCHLORIDE

Base Information

• Chemical Name: GLYCINE-2-13C ETHYL ESTER, HYDROCHLORIDE
• CAS No.: 58420-91-0
• Molecular Formula: C4H10ClNO2
• Molecular Weight: 140.5897
• Mol file: 58420-91-0.mol

Synonyms:GLYCINE-2-13C ETHYL ESTER, HYDROCHLORIDE;(2-Ethoxy-2-oxoethyl)aMMoniuM-2-13C Chloride;AMinoacetic Acid-2-13C Ethyl Ester Hydrochloride;Ethyl 2-AMinoacetate-2-13C Hydrochloride;Ethyl AMinoacetate-2-13C Hydrochloride;Ethyl Glycinate-2-13C Hydrochloride;Glycine-2-13C Ethyl Ester Monohydrochloride

Chemical Property of GLYCINE-2-13C ETHYL ESTER, HYDROCHLORIDE

Chemical Property:

• PSA: 52.32000
• LogP: 1.01050
• Solubility.: Water

Purity/Quality:

97% ^*data from raw suppliers

Glycine-[2-13C] Ethyl Ester, Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Glycine-2-13C Ethyl Ester, Hydrochloride is a labelled Glycine (G615990) ester used as parakeratosis inhibitor and external composition for skin.

Technology Process of GLYCINE-2-13C ETHYL ESTER, HYDROCHLORIDE

There total 2 articles about GLYCINE-2-13C ETHYL ESTER, HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethanol (64-17-5) + 2-(13)C-glycine (20220-62-6) → ethyl 2-(13)C-glycine hydrochloride (58420-91-0)

Guidance literature:

ethanol; 2-⁽¹³⁾C-glycine; With thionyl chloride; at 20 ℃; for 12.5h; Cooling;

With hydrogenchloride;

DOI:10.1007/s00726-010-0808-8

Reference yield: 95.0%

thionyl chloride (7719-09-7) + 2-(13)C-glycine (20220-62-6) → ethyl 2-(13)C-glycine hydrochloride (58420-91-0)

Guidance literature:

In ethanol; for 2h; Reflux;

DOI:10.1021/om400735p

upstream raw materials:

ethanol

2-⁽¹³⁾C-glycine

thionyl chloride