Phosphonic acid bis(trimethylsilylmethyl) ester

Base Information

Chemical Name:Phosphonic acid bis(trimethylsilylmethyl) ester
CAS No.:75203-61-1
Molecular Formula:C₈H₂₃O₃PSi₂
Molecular Weight:254.414
Hs Code.:
Mol file:75203-61-1.mol

Synonyms:Phosphonic acid bis(trimethylsilylmethyl) ester;SDK-9

Suppliers and Price of Phosphonic acid bis(trimethylsilylmethyl) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Phosphonic acid bis(trimethylsilylmethyl) ester

Chemical Property:

PSA：59.00000
LogP:4.00070

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Phosphonic acid bis(trimethylsilylmethyl) ester

There total 1 articles about Phosphonic acid bis(trimethylsilylmethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3219-63-4
(trimethylsilyl)methanol

: 4712-55-4
diphenyl hydrogen phosphite

: 75203-61-1
bis((trimethylsilyl)methyl)phosphonate

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃; for 24h; regioselective reaction;
DOI:10.1021/acs.joc.1c01382

Reference yield:

: 75203-61-1
bis((trimethylsilyl)methyl)phosphonate

: 3-(bis((trimethylsilyl)methoxy)phosphoryl)-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1 h / 0 °C

2: (trimethylsilyl)methylmagnesium chloride / diethyl ether / 1 h / 0 °C

With (trimethylsilyl)methylmagnesium chloride; triethylamine; In diethyl ether; dichloromethane; 2: |Abramov Phosphorylation;
DOI:10.1021/acs.joc.1c01382

Reference yield:

: 75203-61-1
bis((trimethylsilyl)methyl)phosphonate

: bis(trimethylsilyl)methyl (1-benzyl-1H-benzo[d][1,2,3]triazol-4-yl)phosphonate

: bis((trimethylsilyl)methyl) (1-benzyl-1H-benzo[d][1,2,3]triazol-7-yl)phosphonate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 1 h / 0 °C

2: (trimethylsilyl)methylmagnesium chloride / diethyl ether / 1 h / 0 °C

3: cesium fluoride / dichloromethane; acetonitrile / 17 h / 70 °C / Sealed tube; Inert atmosphere

With (trimethylsilyl)methylmagnesium chloride; triethylamine; cesium fluoride; In diethyl ether; dichloromethane; acetonitrile; 2: |Abramov Phosphorylation;
DOI:10.1021/acs.joc.1c01382