4712-55-4

Basic information

• Product Name: DIPHENYL PHOSPHITE
• Synonyms: Diphenyl phosphite, contains varying amounts of phenol and (C6H5O)3P;Phosphonic acid diphenyl;Phosphorous acid diphenyl;Diphenyl Phosphite (contains 5% Phenol at maximum);Diphenyl phosphite, contains varying aMounts of phenol and (C6H5O)3P 5GR;Diphenyl Phosphonate Phosphonic Acid Diphenyl Ester Phosphorous Acid Diphenyl Ester;(contains 5% Phenol at MaxiMuM);Diphenyl Phosphite
• CAS NO: 4712-55-4
• Molecular Formula: C₁₂H₁₁O₃P
• Molecular Weight: 234.19
• EINECS: 225-202-8
• Product Categories: Organic Building Blocks;Organic Phosphates/Phosphites;Phosphorus Compounds
• Mol File: 4712-55-4.mol
• Article Data: 17

Chemical Properties

• Melting Point: 12 °C(lit.)
• Boiling Point: 218-219 °C26 mm Hg(lit.)
• Flash Point: 350 °F
• Appearance: Clear/Liquid
• Density: 1.223 g/mL at 25 °C(lit.)
• Vapor Density: 8.1 (vs air)
• Vapor Pressure: 5 mm Hg ( 140 °C)
• Refractive Index: n20/D 1.558(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• BRN: 2051909
• CAS DataBase Reference: DIPHENYL PHOSPHITE(CAS DataBase Reference)
• NIST Chemistry Reference: DIPHENYL PHOSPHITE(4712-55-4)
• EPA Substance Registry System: DIPHENYL PHOSPHITE(4712-55-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: 1760
• WGK Germany: 3
• F: 21
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 4712-55-4(Hazardous Substances Data)

Usage

Chemical Properties

clear liquid

Uses

Diphenyl Phosphite is a reactant used in the synthesis of α-hydroxyphosphonates and α-hydroxyphosphinates for their antioxidant and antimicrobial activity.

InChI:InChI=1/C12H11O3P/c13-16(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h1-10,16H

Synthetic route

triphenyl phosphite (101-02-0) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
With trifluorormethanesulfonic acid; water at 25℃; Sealed tube;	91%
With phosphonic acid
With water

phenol (108-95-2) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
With trichlorophosphate In toluene at 70℃; for 1.8h; Temperature;	71.3%
With tetraethylammonium iodide; water In acetonitrile at 50℃; electrosynthesis;	20%
With tetraethyldiamidophosphite
With phosphorus trichloride
With trichlorophosphate In toluene at 50℃; for 1.7h;

phenol (108-95-2) → phenyl hydrogen phosphonate (2310-89-6) + diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
With hypophosphorous acid In toluene for 72h; Reflux; Dean-Stark; Inert atmosphere;	A n/a B 63%
With P4O6 In benzene for 1h; Title compound not separated from byproducts;
With P4O6 In benzene for 1h;

Diphenyl phosphorochloridite (5382-00-3) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
With pyridine; diethyl ether; water
Multi-step reaction with 2 steps 1: pyridine 2: hydrogen chloride / 0 °C View Scheme

phosphoric acid diphenyl ester-propyl ester (14862-35-2) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
With hydrogenchloride at 0℃;

triphenyl phosphite (101-02-0) + Diethyl phosphate (598-02-7) → O,O-diethyl O-phenyl phosphate (2510-86-3) + diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
In nitromethane at 30℃;

triphenyl phosphite (101-02-0) + Diethyl phosphate (598-02-7) → diphenyl hydrogen phosphite (4712-55-4) + (Phosphorigsaeure-diphenylester)-(Phosphorsaeure-diethylester)anhydrid

Conditions	Yield
In nitromethane at 30℃; for 8h; Mechanism; Heating; other reactants, other products, other solvents, other temperatures;

triphenyl phosphite (101-02-0) → diphenyl hydrogen phosphite (4712-55-4) + phenol (108-95-2)

Conditions	Yield
With hydrogenchloride In ethanol at 25℃; Rate constant; effect of micelles (sodium lauryl sulfate, dodecylhydrogensulfuric acid, n-tetradecansulfonic acid, p-decyloxybenzenesulfonic acid, cetyltrimethylammonium chloride) and electrolytes;

phenol (108-95-2) → diphenyl hydrogen phosphite (4712-55-4) + phenyl H-phosphonate ammonium salt (54921-72-1)

Conditions	Yield
With P4O6; ammonia 1.) benzene, 1 h; 2.) benzene; Multistep reaction;

C11H15O4P (180906-75-6) + phenol (108-95-2) → diphenyl hydrogen phosphite (4712-55-4)

triphenyl phosphite (101-02-0) → phenyl hydrogen phosphonate (2310-89-6) + phosphoric acid triphenyl ester (115-86-6) + diphenyl hydrogen phosphite (4712-55-4) + phosphorous acid

Conditions	Yield
With oxygen for 2880h; other time;

hydrogenchloride (7647-01-0) + phosphoric acid diphenyl ester-propyl ester (14862-35-2) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
at 0℃;

phenyl H-phosphonate ammonium salt (54921-72-1) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
Multi-step reaction with 2 steps 1: 85 percent / pyridine / acetonitrile View Scheme

N-diisopropylcarbodiimide + Dibenzyl phosphite (17176-77-1) + phenol (108-95-2) → diphenyl hydrogen phosphite (4712-55-4) + 2-hydroxybenzenesulfonamide (3724-14-9)

Conditions	Yield
In pyridine

phenyl hydrogen phosphonate (2310-89-6) + phenol (108-95-2) → diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
Stage #1: phenyl hydrogen phosphonate With phosphorus pentoxide In 1,4-dioxane at 50℃; for 3h; Inert atmosphere; Stage #2: phenol In 1,4-dioxane at 50℃; for 0.333333h; Solvent; Temperature; Inert atmosphere;	61.4 %Spectr.

triphenyl phosphite (101-02-0) → phenyl hydrogen phosphonate (2310-89-6) + diphenyl hydrogen phosphite (4712-55-4)

Conditions	Yield
With [Pt(H2O)2(1,1'-bis(diphenylphosphanyl)octamethylferrocene)](trifluoromethylsulfonate)2; water In tetrahydrofuran at 20℃; for 8h; Catalytic behavior; Mechanism; Reagent/catalyst; Solvent; Inert atmosphere; Schlenk technique; Sealed tube;

diphenyl hydrogen phosphite (4712-55-4) + benzaldehyde (100-52-7) + aniline (62-53-3) → diphenyl α-(phenylamino)benzylphosphonate (3360-68-7)

Conditions	Yield
With mesoporous silica-sulfonic acid produced from sugarcane bagasse ash In dichloromethane at 20℃; for 0.333333h; Solvent; Concentration; Reagent/catalyst; Kabachnik-Fields Reaction; Green chemistry;	100%
With ytterbium(III) chloride In acetonitrile at 20℃; for 24h;	98%
With zinc(II) L-prolinate complex In dichloromethane at 20℃; for 0.333333h; Catalytic behavior; Solvent; Kabachnik-Fields Reaction;	98%

octanol (111-87-5) + diphenyl hydrogen phosphite (4712-55-4) + triethylamine (121-44-8) → triethylammonium octyl hydrogen phosphonate

Conditions	Yield
In pyridine at 20℃; for 0.5h;	100%

(2,3-dihydroxy-4-methoxy-phenyl)-(1,2,3-trimethoxy-8,9-dihydro-7H-benzocyclohepten-5-yl)-methanone + diphenyl hydrogen phosphite (4712-55-4) → C50H50O13P2

Conditions	Yield
With dmap; N-ethyl-N,N-diisopropylamine In tetrachloromethane; acetonitrile at -20℃;	100%

diphenyl hydrogen phosphite (4712-55-4) + 4-nitrobenzaldehdye (555-16-8) + aniline (62-53-3) → diphenyl 1-phenylamino-1-(4-nitrophenyl)methanephosphonate (3360-69-8)

Conditions	Yield
With C2O4(2-)*2Ce(3+)*2C5H9NO2*(x)H2O In toluene at 20℃; for 0.166667h; Kabachnik-Fields Reaction;	99%
With zinc(II) L-prolinate complex In dichloromethane at 20℃; for 0.75h; Kabachnik-Fields Reaction;	95%
at 20℃; for 0.0833333h; Kabachnik-Fields Reaction; Ionic liquid;	69%
(i) EtOH, (ii) /BRN= 2051909/; Multistep reaction;

1-benzyl-1H-pyrrole-2,5-dione (1631-26-1) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-benzyl-2,5-dioxopyrrolidin-3-ylphosphonate

Conditions	Yield
With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine In toluene at 20℃; for 0.0833333h;	99%

(bicyclo[2.2.1]hepta-2,5-diene)tetracarbonylmolybdenum(0) (12146-37-1, 124717-04-0) + dichloro(2,4,6-tribromophenoxy)(1,2-diphenoxy)phosphorane (500561-67-1) + diphenyl hydrogen phosphite (4712-55-4) → cis-tetracarbonylbis(diphenylchlorophosphite)molybdenum(0) (500561-81-9)

Conditions	Yield
In benzene under N2; phosphite (1 equiv.) added to benzene soln. of phosphorane; reacted for 24 h; solid Mo complex (0.5 equiv.) added; 1 h; monitored by (31)P NMR spectra;	99%

N-[(4-methylphenyl)methylidene]-(6-methyl-2-pyridinesulfonamide) (1155765-86-8) + diphenyl hydrogen phosphite (4712-55-4) → (S)-diphenyl [(6-methyl-2-pyridinesulfonyl)amino-(4-methylphenyl)methyl]phosphonate (1155765-39-1)

Conditions	Yield
With dihydroquinine In toluene at -78℃; for 1h; optical yield given as %ee;	99%

N-[(4-methoxyphenyl)methylidene]-(6-methyl-2-pyridinesulfonamide) (1155765-88-0) + diphenyl hydrogen phosphite (4712-55-4) → (S)-diphenyl [(6-methyl-2-pyridinesulfonyl)amino-(4-methylphenyl)methyl]phosphonate (1155765-39-1)

Conditions	Yield
With dihydroquinine In toluene at -78℃; for 1h; optical yield given as %ee;	99%

N-(1-naphthylmethylidene)-(6-methyl-2-pyridinesulfonamide) (1155765-95-9) + diphenyl hydrogen phosphite (4712-55-4) → (R)-diphenyl [(6-methyl-2-pyridinesulfonyl)amino-(1-naphthyl)methyl]phosphonate (1155765-67-5)

Conditions	Yield
With hydroquinidine In toluene at -78℃; for 1h; optical yield given as %ee;	99%

N-(2-naphthylmethylidene)-(6-methyl-2-pyridinesulfonamide) (1155765-96-0) + diphenyl hydrogen phosphite (4712-55-4) → (R)-diphenyl [(6-methyl-2-pyridinesulfonyl)amino-(2-naphthyl)methyl]phosphonate (1155765-69-7)

Conditions	Yield
With hydroquinidine In toluene at -78℃; for 1h; optical yield given as %ee;	99%

N-benzylidene-(6-methyl-2-pyridine)sulfonamide (1155765-35-7) + diphenyl hydrogen phosphite (4712-55-4) → (S)-diphenyl (6-methyl-2-pyridylsulfonylamino)phenylmethylphosphonate (1155765-37-9)

Conditions	Yield
With dihydroquinine In toluene at -78℃; for 1h; optical yield given as %ee;	99%

N-benzylidene-(6-methyl-2-pyridine)sulfonamide (1155765-35-7) + diphenyl hydrogen phosphite (4712-55-4) → (R)-diphenyl (6-methyl-2-pyridylsulfonylamino)phenylmethylphosphonate (1155765-82-4)

Conditions	Yield
With hydroquinidine In toluene at -40℃; for 1h; optical yield given as %ee;	99%

nitrostyrene (5153-67-3) + diphenyl hydrogen phosphite (4712-55-4) → (2-nitro-1-phenyl-ethyl)-phosphonic acid diphenyl ester

Conditions	Yield
With 3-((1R,2R)-2-(piperidin-1-yl)cyclohexylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione In dichloromethane at 0℃; Michael condensation; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

3-[(E)-2-nitroeth-1-enyl]-1H-indole (3156-51-2, 51870-94-1) + diphenyl hydrogen phosphite (4712-55-4) → (R)-diphenyl 1-(1H-indol-3-yl)-2-nitroethylphosphonate (1211565-18-2)

Conditions	Yield
With 3-((1R,2R)-2-(piperidin-1-yl)cyclohexylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione In dichloromethane at 0℃; for 0.25h; Michael condensation; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

5-((E)-2-nitroethenyl)-1,3-benzodioxole (1485-00-3, 22568-48-5) + diphenyl hydrogen phosphite (4712-55-4) → (1-benzo[1,3]dioxol-5-yl-2-nitro-ethyl)-phosphonic acid diphenyl ester

Conditions	Yield
With 3-((1R,2R)-2-(piperidin-1-yl)cyclohexylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione In dichloromethane at 0℃; Michael condensation; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

diphenyl hydrogen phosphite (4712-55-4) + (E)-2-(2-nitrovinyl)naphthalene (21461-46-1, 37629-37-1) → (R)-diphenyl 1-(2-naphthyl)-2-nitroethylphosphonate (1211565-17-1)

Conditions	Yield
With 3-((1R,2R)-2-(piperidin-1-yl)cyclohexylamino)-4-(4-(trifluoromethyl)phenylamino)cyclobut-3-ene-1,2-dione In dichloromethane at 0℃; Michael condensation; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(4-methoxyphenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (327175-82-6) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(p-methoxyphenyl)ethylphosphonate (1202246-78-3)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 140h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(4-chlorophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (327175-80-4) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(p-chlorophenyl)ethylphosphonate (1202246-79-4)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 51h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(4-chlorophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (327175-80-4) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(p-chlorophenyl)ethylphosphonate (1202246-95-4)

Conditions	Yield
With sodium carbonate; hydroquinidine In toluene at -20℃; for 51h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(4-bromophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (1202246-66-9) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(p-bromophenyl)ethylphosphonate (1202246-96-5)

Conditions	Yield
With sodium carbonate; hydroquinidine In toluene at -20℃; for 86h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(4-fluorophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (1202246-67-0) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(p-fluorophenyl)ethylphosphonate (1202246-81-8)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 72h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(3-chlorophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (1202246-69-2) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(m-chlorophenyl)ethylphosphonate (1202246-82-9)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 67h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(3-chlorophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (1202246-69-2) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(m-chlorophenyl)ethylphosphonate (1202246-98-7)

Conditions	Yield
With sodium carbonate; hydroquinidine In toluene at -20℃; for 67h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(3-bromophenyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (1202246-70-5) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(m-bromophenyl)ethylphosphonate (1202246-83-0)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 85h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-{1-(2-naphthyl)ethylidene}-2,4,6-trimethylphenylsulfonamide (327175-83-7) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-(2-naphthyl)ethylphosphonate (1202246-85-2)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 84h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-(1-phenylethylidene)-2,4,6-trimethylphenylsulfonamide (327175-79-1) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-phenylethylphosphonate (1202246-58-9)

Conditions	Yield
With sodium carbonate; dihydroquinine In toluene at -20℃; for 60h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

N-(1-phenylethylidene)-2,4,6-trimethylphenylsulfonamide (327175-79-1) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl 1-(2,4,6-trimethylphenylsulfonylamino)-1-phenylethylphosphonate (1202246-63-6)

Conditions	Yield
With sodium carbonate; hydroquinidine In toluene at -20℃; for 60h; Pudovik reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

isoquinoline (119-65-3) + diphenyl hydrogen phosphite (4712-55-4) + 2-chloro-4-isocyanato-1-methylbenzene (28479-22-3) → diphenyl {2-{[(3-chloro-4-methylphenyl)amino]carbonyl}-1,2-dihydroisoquinolin-1-yl}phosphonate (1229062-04-7)

Conditions	Yield
at 20℃; for 0.0666667h;	99%

N-(2-furylmethylidene)-2-methylaniline + diphenyl hydrogen phosphite (4712-55-4) → diphenyl (2-furyl)(2-methylphenylamino)methylphosphonate (1378426-62-0)

Conditions	Yield
With trifluoroacetic acid In acetonitrile at 20 - 80℃; for 72h;	99%

furfurylidene-p-toluidine (13060-72-5) + diphenyl hydrogen phosphite (4712-55-4) → diphenyl (2-furyl)(4-methylphenylamino)methylphosphonate (1378426-66-4)

Conditions	Yield
With trifluoroacetic acid In acetonitrile at 20 - 80℃; for 72h;	99%

Upstream product

• 5382-00-3 Diphenyl phosphorochloridite 
• 108-95-2 phenol 
• 101-02-0 triphenyl phosphite 
• 7647-01-0 hydrogenchloride 
• 14862-35-2 phosphoric acid diphenyl ester-propyl ester 
• 2310-89-6 phenyl hydrogen phosphonate 
• 17176-77-1 Dibenzyl phosphite 
• 54921-72-1 phenyl H-phosphonate ammonium salt 
• 180906-75-6 C₁₁H₁₅O₄P 
• 598-02-7 Diethyl phosphate 

Downstream Products

• 2015-56-7 diphenylphosphoroamidate 
• 52364-32-6 (hydroxy-phenyl-methyl)-phosphonic acid diphenyl ester 
• 54944-08-0 [1-(N'-Cyclohexylidene-hydrazino)-cyclohexyl]-phosphonic acid diphenyl ester 
• 49802-24-6 Diphenyl-N-1-adamantylphosphoramidat 
• 57078-63-4 (1-{N'-[1-Phenyl-meth-(Z)-ylidene]-hydrazino}-cyclohexyl)-phosphonic acid diphenyl ester 
• 54944-09-1 (1-Methyl-1-{N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-ethyl)-phosphonic acid diphenyl ester 
• 2310-89-6 phenyl hydrogen phosphonate 
• 16757-62-3 diphenyl phosphoryl hydroxylamine 
• 54921-72-1 phenyl H-phosphonate ammonium salt 
• 34670-53-6 tetraphenyl propane-1,3-diylbis(phosphoramidate) 
• 54944-06-8 (Phenyl-{N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-methyl)-phosphonic acid diphenyl ester 
• 54944-14-8 Tetraphenyl(hydrazobisisopropyliden)bisphosphonat 
• 146399-46-4 Phosphorsaeure-diphenyl-(2-hydroxy-3,4,5,6-tetrachlorphenyl)ester 
• 841-46-3 ethyl diphenyl phosphate 

Relevant articles and documents

Sulfur phosphate compound, non-aqueous lithium ion battery electrolyte containing sulfur phosphate compound and lithium ion battery

The invention discloses a thiophosphate compound, a synthesis method and a non-aqueous electrolyte. After the compound is applied to a battery with the non-aqueous electrolyte, even if the battery isunder high voltage, an electrode/electrolyte interface of a lithium ion battery is effectively improved, so that an electrode surface film is stabilized, side reactions are reduced, the stability of the battery under high temperature and high voltage is improved, and the cycling stability of the battery is improved, and meanwhile, the self-extinguishing time of the non-aqueous electrolyte after combustion is shortened, the flame retardance is improved, and the safety performance of the battery is improved.

METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing an organophosphorus compound which has excellent energy efficiency without containing a halogenated alkyl or a by-product derived from a halogenated alkyl. SOLUTION: There is provided a method for producing an organophosphorus compound by reacting a trivalent organophosphorus compound represented by the following general formula (1) in the presence of a super strong acid and/or at least one acid catalyst containing a solid superstrong acid catalyst to generate a pentavalent organophosphorus compound represented by the following general formula. (where Z1 represents OR2 or R2; Z2 represents OR3 or R3; R1, R2 and R3 represent an alkyl group, an alkenyl group or the like; when R2 and R3 are an alkyl group or the like, R2 and R3 may be bonded to each other to form a cyclic structure; and R1 may be a hydrogen atom.) SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

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Cationic phosphametallocene-based platinum(II) aqua complexes were used as efficient precatalysts for the hydrolysis of aromatic and aliphatic tertiary phosphites under neutral reaction conditions at room temperature, leading to the selective cleavage of one P-O bond of the phosphite. NMR labeling experiments combined with stoichiometric model reactions and theoretical density functional theory calculations, performed with the appropriate model compounds, shed light on the operative catalytic cycle, which comprises intramolecular water molecule transfer to the cis-coordinated phosphite molecule.