(S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one

Base Information

Chemical Name:(S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one
CAS No.:1420627-35-5
Molecular Formula:C₁₆H₁₄ClN₃O
Molecular Weight:299.76
Hs Code.:

Synonyms:(S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one;2-[(1S)-1-aminoethyl]-5-chloro-3-phenyl-3,4-dihydroquinazolin-4-one

Suppliers and Price of (S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of (S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one

There total 10 articles about (S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1441309-09-6
tert-butyl (S)-(1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazoline-2-yl)ethyl)carbamate

: 1420627-35-5
(S)-2-(1-aminoethyl)-5-chloro-3-phenylquinazoline-4(3H)-one

Guidance literature:: With hydrogenchloride; In water; ethyl acetate; at 20 ℃; for 40h;

Reference yield:

: 5344-49-0
2-chloro-6-nitrobenzoic acid

: 1420627-35-5
(S)-2-(1-aminoethyl)-5-chloro-3-phenylquinazoline-4(3H)-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 1.5 h / Reflux

1.2: 10 - 20 °C

2.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 2 h / Reflux

2.2: 0 - 20 °C

3.1: zinc; acetic acid / 4 h / 20 °C

4.1: hydrogenchloride / methanol / 2 h / 20 °C

With hydrogenchloride; thionyl chloride; acetic acid; N,N-dimethyl-formamide; zinc; In methanol; toluene;

Reference yield:

: 2-chloro-6-nitro-benzoic acid anilide

: 1420627-35-5
(S)-2-(1-aminoethyl)-5-chloro-3-phenylquinazoline-4(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride; N,N-dimethyl-formamide / toluene / 2 h / Reflux

1.2: 0 - 20 °C

2.1: zinc; acetic acid / 4 h / 20 °C

3.1: hydrogenchloride / methanol / 2 h / 20 °C

With hydrogenchloride; thionyl chloride; acetic acid; N,N-dimethyl-formamide; zinc; In methanol; toluene;