5-CHLORO-3,1-BENZOXAZIN-2,4-DIONE

Base Information

• Chemical Name: 5-CHLORO-3,1-BENZOXAZIN-2,4-DIONE
• CAS No.: 20829-96-3
• Molecular Formula: C8H4ClNO3
• Molecular Weight: 197.578
• Hs Code.: 2934999090
• Mol file: 20829-96-3.mol

Synonyms:5-Chloro-3,1-benzoxazin-2,4-dione;5-Chloro-1h-benzo[d][1,3]oxazine-2,4-dione;

Chemical Property of 5-CHLORO-3,1-BENZOXAZIN-2,4-DIONE

Chemical Property:

• Melting Point: 272.5-272.9 °C
• PKA: 10.27±0.20(Predicted)
• PSA: 63.33000
• Density: 1.54 g/cm³
• LogP: 1.54700
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5-Chloro-1H-benzo[d][1,3]oxazine-2,4-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-CHLORO-3,1-BENZOXAZIN-2,4-DIONE

There total 9 articles about 5-CHLORO-3,1-BENZOXAZIN-2,4-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

phosgene (75-44-5) + 2-chloro-6-aminobenzoic acid (2148-56-3) → 5-chloro-1H-benzo[d][1,3]oxazine-2,4-dione (20829-96-3)

Guidance literature:

In 1,4-dioxane; at 12 - 20 ℃;

DOI:10.1021/op700001c

Reference yield: 99.0%

bis(trichloromethyl) carbonate (32315-10-9) + 2-chloro-6-aminobenzoic acid (2148-56-3) → 5-chloro-1H-benzo[d][1,3]oxazine-2,4-dione (20829-96-3)

Guidance literature:

In 1,4-dioxane; for 2h; Reflux;

Reference yield: 97.26%

C13H10ClNO6 → 5-chloro-1H-benzo[d][1,3]oxazine-2,4-dione (20829-96-3)

Guidance literature:

In water; at 25 - 70 ℃; for 17h; Temperature;

upstream raw materials:

phosgene

2-chloro-6-aminobenzoic acid

bis(trichloromethyl) carbonate

acetyl chloride

Downstream raw materials:

methyl 6-chloroanthranilate

1,9-Dichloro-indolo[2,1-b]quinazoline-6,12-dione

8-Chloro-1-[(E)-3-dimethylamino-propylimino]-3-(4-trifluoromethyl-phenyl)-1,3,4,10-tetrahydro-2H-acridin-9-one

1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxylic acid methyl ester