Benzyl (1-amino-1-oxopropan-2-yl)carbamate

Base Information

Chemical Name:Benzyl (1-amino-1-oxopropan-2-yl)carbamate
CAS No.:2503-29-9
Molecular Formula:C₁₁H₁₄N₂O₃
Molecular Weight:222.244
Hs Code.:
DSSTox Substance ID:DTXSID901212497
Nikkaji Number:J1.573.826J

Synonyms:2-(Cbz-amino)propanamide;2503-29-9;Benzyl (1-amino-1-oxopropan-2-yl)carbamate;Z-Ala-NH;Z-D-Ala-NH;benzyl N-(1-amino-1-oxopropan-2-yl)carbamate;SCHEMBL591894;DTXSID901212497;CAA50329;CARBOBENZYLOXY-DL-ALANINAMIDE;AC5728;MFCD00136699;AKOS022183676;2-[(Benzyloxycarbonyl)amino]propanamide;BS-22128;SY021103;Benzyl(1-amino-1-oxopropan-2-yl)carbamate;BENZYL N-(1-CARBAMOYLETHYL)CARBAMATE;CS-0450118;FT-0697544;A877727;Phenylmethyl N-(2-amino-1-methyl-2-oxoethyl)carbamate

Suppliers and Price of Benzyl (1-amino-1-oxopropan-2-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of Benzyl (1-amino-1-oxopropan-2-yl)carbamate

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:222.10044231
Heavy Atom Count:16
Complexity:250

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)N)NC(=O)OCC1=CC=CC=C1

Technology Process of Benzyl (1-amino-1-oxopropan-2-yl)carbamate

There total 4 articles about Benzyl (1-amino-1-oxopropan-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4132-86-9,26607-51-2,1142-20-7
N-benzyloxycarbonylalanine

: 2503-29-9
(2-amino-1-methyl-2-oxoethyl)carbamic acid phenylmethyl ester

Guidance literature:: Multistep reaction; (i) carbonyldiimidazole, THF, (ii) HN(SiMe₃)2, (iii) (hydrolysis);

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 2503-29-9
(2-amino-1-methyl-2-oxoethyl)carbamic acid phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / H₂O

2: ethyl chloroformate; aq. ammonia; triethylamine / tetrahydrofuran / 0.5 h / 0 °C

With ammonium hydroxide; chloroformic acid ethyl ester; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; water;
DOI:10.1021/ol0708020

Reference yield:

: 1142-20-7
N-benzyloxycarbonyl-L-alanine

: 2503-29-9,13139-27-0,69531-18-6,151378-81-3
(1-Carbamoyl-ethyl)-carbamic acid benzyl ester

Guidance literature:: With tetrahydrofuran; ammonia; chloroformic acid ethyl ester; triethylamine; Yield given. Multistep reaction; 1.)-8 deg C, 10 min 2.)r.t., 3 h;
DOI:10.1002/jhet.5570180829