5-FLUORO-2'-O-METHYL-4-THIOURIDINE

Base Information

• Chemical Name: 5-FLUORO-2'-O-METHYL-4-THIOURIDINE
• CAS No.: 869355-51-1
• Molecular Formula: C10H13FN2O5S
• Molecular Weight: 292.288
• Mol file: 869355-51-1.mol

Synonyms:5-FLUORO-2'-O-METHYL-4-THIOURIDINE

Chemical Property of 5-FLUORO-2'-O-METHYL-4-THIOURIDINE

Chemical Property:

• PSA: 128.80000
• LogP: -0.68940

Purity/Quality:

95% ^*data from raw suppliers

5-Fluoro-2’-O-methyl-4-thiouridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Fluoro-2’-O-methyl-4-thiouridine is a reagent used in the formation of a highly efficient fluorescent photoadduct of DNA duplexes.

Technology Process of 5-FLUORO-2'-O-METHYL-4-THIOURIDINE

There total 4 articles about 5-FLUORO-2'-O-METHYL-4-THIOURIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C98H122FN40O56P9S → 2-deoxyinosine (890-38-0) + 5-fluoro-4-deoxy-4-thio-2'-O-methyluridine (869355-51-1) + 2'-Deoxyguanosine (961-07-9) + 2'-Deoxycytidine (951-77-9) + thymidine (50-89-5,28854-96-8,3545-96-8,50-88-4) + 2'-deoxy-D-adenosine (958-09-8,7005-15-4)

Guidance literature:

With Crotalus adamanteus venom phosphodiesterase I; bovine intestinal mucosa alkaline phosphatase; water; magnesium chloride; at 37 ℃; for 18h; pH=7; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.bmc.2011.08.035

Reference yield:

C98H122FN40O56P9S → 2-deoxyinosine (890-38-0) + 5-fluoro-4-deoxy-4-thio-2'-O-methyluridine (869355-51-1) + 2'-Deoxyguanosine (961-07-9) + 2'-Deoxycytidine (951-77-9) + thymidine (50-89-5,28854-96-8,3545-96-8,50-88-4) + 2'-deoxy-D-adenosine (958-09-8,7005-15-4)

Guidance literature:

With Crotalus adamanteus venom phosphodiesterase I; bovine intestinal mucosa alkaline phosphatase; water; magnesium chloride; at 37 ℃; for 18h; pH=7; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.bmc.2011.08.035

Reference yield:

C99H124FN36O58P9S → 2-deoxyinosine (890-38-0) + 5-fluoro-4-deoxy-4-thio-2'-O-methyluridine (869355-51-1) + 2'-Deoxyguanosine (961-07-9) + 2'-Deoxycytidine (951-77-9) + thymidine (50-89-5,28854-96-8,3545-96-8,50-88-4) + 2'-deoxy-D-adenosine (958-09-8,7005-15-4)

Guidance literature:

With Crotalus adamanteus venom phosphodiesterase I; bovine intestinal mucosa alkaline phosphatase; water; magnesium chloride; at 37 ℃; for 18h; pH=7; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.bmc.2011.08.035

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