N-hydroxy-2,3-dimethoxybenzamide

Base Information

• Chemical Name: N-hydroxy-2,3-dimethoxybenzamide
• CAS No.: 343773-22-8
• Molecular Formula: C9H11NO4
• Molecular Weight: 197.191
• Mol file: 343773-22-8.mol

Synonyms:N-hydroxy-2,3-dimethoxybenzamide

Chemical Property of N-hydroxy-2,3-dimethoxybenzamide

Chemical Property:

• PSA: 67.79000
• LogP: 1.21370

Purity/Quality:

97% ^*data from raw suppliers

N-Hydroxy-2,3-dimethoxybenzamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-hydroxy-2,3-dimethoxybenzamide

There total 4 articles about N-hydroxy-2,3-dimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

→ N-hydroxy-2,3-dimethoxybenzamide (343773-22-8)

Guidance literature:

With potassium hydroxide; hydroxylamine; In methanol; at 20 ℃; for 12h; pH=10;

DOI:10.1039/b822806j

Reference yield: 70.0%

methyl 2,3-dimethoxybenzoate (2150-42-7) → N-hydroxy-2,3-dimethoxybenzamide (343773-22-8)

Guidance literature:

With hydroxylamine hydrochloride; potassium hydroxide; In methanol; at 20 ℃; for 12h; pH=10;

DOI:10.1039/c6ob01178k

Reference yield:

2,3-dimethoxybenzoic acid (1521-38-6) → N-hydroxy-2,3-dimethoxybenzamide (343773-22-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.08 h / 20 °C / Milling

2: hydroxylamine hydrochloride / 0.75 h / 20 °C / Milling

With hydroxylamine hydrochloride;

DOI:10.1002/adsc.201600350

upstream raw materials:

(2,3-Dimethoxy-phenyl)-imidazol-1-yl-methanone

2,3-dimethoxybenzoic acid

methyl 2,3-dimethoxybenzoate

Downstream raw materials:

2,3-dimethoxyaniline