1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea

Base Information

• Chemical Name: 1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea
• CAS No.: 508186-14-9
• Molecular Formula: C20H18N4O2S2
• Molecular Weight: 410.51
• Mol file: 508186-14-9.mol

Synonyms:1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea

Chemical Property of 1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea

Chemical Property:

• Boiling Point: 539.3±50.0 °C(Predicted)
• PKA: 12.34±0.43(Predicted)
• PSA: 132.62000
• Density: 1.364±0.06 g/cm3(Predicted)
• LogP: 5.31860

Purity/Quality:

99% ^*data from raw suppliers

Ac-CoA Synthase Inhibitor - CAS 508186-14-9 - Calbiochem ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea

There total 2 articles about 1-(2,3-Di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2,3-di(thiophen-2-yl)quinoxalin-6-amine (354774-58-6) + 2-methoxyethylamine (109-85-3) → 1-(2,3-di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea (508186-14-9)

Guidance literature:

2,3-di(thiophen-2-yl)quinoxalin-6-amine; With bis(trichloromethyl) carbonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 4h;

2-methoxyethylamine; In dichloromethane; at 20 ℃; for 16h;

Reference yield: 50.0%

bis(trichloromethyl) carbonate (32315-10-9) + 2,3-di(thiophen-2-yl)quinoxalin-6-amine (354774-58-6) + 2-methoxyethylamine (109-85-3) → 1-(2,3-di(thiophen-2-yl)quinoxalin-6-yl)-3-(2-methoxyethyl)urea (508186-14-9)

Guidance literature:

bis(trichloromethyl) carbonate; 2,3-di(thiophen-2-yl)quinoxalin-6-amine; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 4h;

2-methoxyethylamine; In dichloromethane; at 20 ℃; for 16h;

upstream raw materials:

bis(trichloromethyl) carbonate

2,3-di(thiophen-2-yl)quinoxalin-6-amine

2-methoxyethylamine