1-Piperidinecarboxylic acid, 4-(4-forMyl-1H-1,2,3-triazol-1-yl)-, 1,1-diMethylethyl ester

Base Information

• Chemical Name: 1-Piperidinecarboxylic acid, 4-(4-forMyl-1H-1,2,3-triazol-1-yl)-, 1,1-diMethylethyl ester
• CAS No.: 915370-15-9
• Molecular Formula: C₁₃H₂₀N₄O₃
• Molecular Weight: 280.327
• Mol file: 915370-15-9.mol

Synonyms:1-Piperidinecarboxylic acid, 4-(4-forMyl-1H-1,2,3-triazol-1-yl)-, 1,1-diMethylethyl ester

Chemical Property of 1-Piperidinecarboxylic acid, 4-(4-forMyl-1H-1,2,3-triazol-1-yl)-, 1,1-diMethylethyl ester

Chemical Property:

• Vapor Pressure: 7.09E-08mmHg at 25°C
• Boiling Point: 438.1°C at 760 mmHg
• Flash Point: 218.8°C
• PSA: 77.32000
• Density: 1.27g/cm³
• LogP: 1.60050

Purity/Quality:

≥95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Piperidinecarboxylic acid, 4-(4-forMyl-1H-1,2,3-triazol-1-yl)-, 1,1-diMethylethyl ester

There total 1 articles about 1-Piperidinecarboxylic acid, 4-(4-forMyl-1H-1,2,3-triazol-1-yl)-, 1,1-diMethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyl 4-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate (1229516-67-9) → tert-butyl 4-(4-formyl-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate (915370-15-9)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; at -78 ℃;

DOI:10.1016/j.bmcl.2010.03.044

upstream raw materials:

tert-butyl 4-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate

Refernces