Chlorodiphenylacetic acid

Base Information

Chemical Name:Chlorodiphenylacetic acid
CAS No.:7475-56-1
Molecular Formula:C14H11 Cl O2
Molecular Weight:246.693
Hs Code.:2916399090
European Community (EC) Number:231-277-8
NSC Number:400464
UNII:EBK7UX6RTX
DSSTox Substance ID:DTXSID00225731
Nikkaji Number:J278.880B
Wikidata:Q83104847
ChEMBL ID:CHEMBL1741929
Mol file:7475-56-1.mol

Synonyms:Chlorodiphenylacetic acid;7475-56-1;2-chloro-2,2-diphenylacetic acid;chloro(diphenyl)acetic acid;Benzeneacetic acid, a-chloro-a-phenyl-;NSC400464;NSC-400464;EINECS 231-277-8;alpha-Chloro-alpha-phenylbenzeneacetic acid;Diphenylchloressigsaure;EBK7UX6RTX;Chlorodiphenyl acetic acid;NCIStruc1_000674;NCIStruc2_001221;Acetic acid, chlorodiphenyl-;SCHEMBL41202;CHEMBL1741929;DTXSID00225731;CCG-37810;NCGC00014889;NCI400464;NSC 400464;2-Chloro-alpha-phenylphenyl-acetic acid;NCGC00014889-02;NCGC00097990-01;NCI60_003739;Benzeneacetic acid, alpha-chloro-alpha-phenyl-;J-509008

Suppliers and Price of Chlorodiphenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Chlorodiphenylacetic acid

Chemical Property:

Vapor Pressure:3.23E-06mmHg at 25°C
Boiling Point:372.7°C at 760 mmHg
Flash Point:179.2°C
PSA：37.30000
Density:1.283g/cm³
LogP:3.25360
Solubility.:Dichloromethane; DMSO
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:246.0447573
Heavy Atom Count:17
Complexity:247

Purity/Quality:: 99.5% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CC=C2)(C(=O)O)Cl
Uses Chlorodiphenylacetic Acid is an intermediate in synthesizing Estocin (E668500), an opioid analgesic and is closely related to Benactyzine Hydrochloride (B119600).

Technology Process of Chlorodiphenylacetic acid

There total 15 articles about Chlorodiphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 76-93-7
Benzilic acid

: 7475-56-1
chloro(diphenyl)acetic acid

Guidance literature:: With acetyl chloride; In dichloromethane;
DOI:10.1039/c2ob26498f

Reference yield: 90.0%

: 117-34-0
2,2-diphenylacetic acid

: 7475-56-1
chloro(diphenyl)acetic acid

Guidance literature:: With chlorine; In carbon disulfide; at 28 - 32 ℃; for 6h; Irradiation;

Reference yield: 80.0%

: 76-93-7
Benzilic acid

: 7475-56-1
chloro(diphenyl)acetic acid

: 3808-00-2
α-acetoxy-α-phenylbenzeneacetic acid

Guidance literature:: With acetyl chloride; In dichloromethane; Yields of byproduct given; 1.) 0 deg C, 2.) room temperature, 1 h;
DOI:10.1016/S0040-4020(01)80747-X