Estetrol 17-Acetate

Base Information

Chemical Name:Estetrol 17-Acetate
CAS No.:690996-23-7
Molecular Formula:C₂₀H₂₆O₅
Molecular Weight:346.423
Hs Code.:
Mol file:690996-23-7.mol

Synonyms:Estetrol 17-Acetate;(15α,16α,17β)-Estra-1,3,5(10)-triene-3,15,16,17-tetrol 17-Acetate

Suppliers and Price of Estetrol 17-Acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Estetrol17-Acetate
25mg
$ 690.00

TRC
Estetrol17-Acetate
2mg
$ 70.00

Total 4 raw suppliers

Chemical Property of Estetrol 17-Acetate

Chemical Property:

PSA：86.99000
LogP:2.12160
Solubility.:Methanol

Purity/Quality:

97% ^*data from raw suppliers

Estetrol17-Acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Protected Estetrol.

Technology Process of Estetrol 17-Acetate

There total 14 articles about Estetrol 17-Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 690996-24-8
17-acetyl-3-benzyl estetrol

: 690996-23-7
17-acetyl estetrol

Guidance literature:: With hydrogen; 10% palladium on activated carbon; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield: 90.0%

: 690996-24-8
17-acetyl-3-benzyl estetrol

: 690996-23-7
17-acetyl estetrol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield:

: 53-16-7
Estrone

: 690996-23-7
17-acetyl estetrol

Guidance literature:: Multi-step reaction with 7 steps

1.1: potassium carbonate / dichloromethane; methanol / 16 h / Reflux

2.1: triethylamine / dichloromethane / 1 h / 20 °C

3.1: oxygen / palladium diacetate / dichloromethane; dimethyl sulfoxide / 35 °C

4.1: cerium(III) chloride heptahydrate / tetrahydrofuran; methanol / 1 h / 20 °C

4.2: 2 h / 0 - 8 °C

5.1: pyridine / dmap / 2 h / 20 °C

6.1: trimethylamine-N-oxide / ~5percent w/w OsO₄ on PVP / tetrahydrofuran / 50 °C

7.1: hydrogen / palladium 10% on activated carbon / methanol / 24 h / 20 °C / 760.05 Torr

With pyridine; trimethylamine-N-oxide; cerium(III) chloride heptahydrate; hydrogen; oxygen; potassium carbonate; triethylamine; dmap; palladium 10% on activated carbon; palladium diacetate; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;