(S)-3-Chloro-pyrrolidine hydrochloride

Base Information

• Chemical Name: (S)-3-Chloro-pyrrolidine hydrochloride
• CAS No.: 1072227-55-4
• Molecular Formula: C4H9Cl2N
• Molecular Weight: 142.02696
• Hs Code.: 2933990090
• Mol file: 1072227-55-4.mol

Synonyms:(S)-3-Chloro-pyrrolidine hydrochloride;(3S)-3-chloro-Pyrrolidine hydrochloride

Chemical Property of (S)-3-Chloro-pyrrolidine hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 1.71790

Purity/Quality:

97% ^*data from raw suppliers

(S)-3-chloropyrrolidineHCl 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-3-Chloro-pyrrolidine hydrochloride

There total 1 articles about (S)-3-Chloro-pyrrolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-3-hydroxypyrrolidine hydrochloride (104706-47-0,111810-68-5) → (S)-3-chloro-pyrrolidine hydrochloride (1072227-55-4,10603-47-1,1354009-92-9)

Guidance literature:

With thionyl chloride; In toluene; at 25 - 55 ℃; for 17h;

Reference yield:

(S)-3-chloro-pyrrolidine hydrochloride (1072227-55-4,10603-47-1,1354009-92-9) + p-toluenesulfonyl chloride (98-59-9) → (+)-3-chloro-1-(toluene-4-sulfonyl)-pyrrolidine (1072227-58-7)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 30 ℃; for 24h;

upstream raw materials:

(R)-3-hydroxypyrrolidine hydrochloride

Downstream raw materials:

(+)-3-chloro-1-(toluene-4-sulfonyl)-pyrrolidine