(R)-3-Hydroxypyrrolidine hydrochloride

Base Information Edit

Chemical Name:(R)-3-Hydroxypyrrolidine hydrochloride
CAS No.:104706-47-0
Molecular Formula:C4H9NO^.HCl
Molecular Weight:123.582
Hs Code.:DERIVATION
DSSTox Substance ID:DTXSID90374747
Mol file:104706-47-0.mol

Synonyms:104706-47-0;(R)-3-Hydroxypyrrolidine hydrochloride;(R)-(-)-3-Pyrrolidinol hydrochloride;(r)-pyrrolidin-3-ol hydrochloride;(R)-3-Hydroxypyrrolidine HCl;(3R)-pyrrolidin-3-ol hydrochloride;(R)-3-Pyrrolidinol hydrochloride;(R)-(-)-3-Hydroxypyrrolidine Hydrochloride;(3R)-pyrrolidin-3-ol;hydrochloride;(3R)-PYRROLIDIN-3-OL, HCL;(3r)-3-hydroxypyrrolidine hydrochloride;r-3-hydroxypyrrolidine hydrochloride;(3R)-3-Pyrrolidinol hydrochloride (1:1);(S)-3-Hydroxypyrrolidine HCl;r-3-hydroxypyrrolidine-hcl;MFCD00191570;(R)-3-Hydroxypyrrolidinehydrochloride;3r-pyrrolidinol hydrochloride;SCHEMBL16919;(R)-(+)-3-Pyrrolidinol HCL;DTXSID90374747;QPMSJEFZULFYTB-PGMHMLKASA-N;(R)-3-hydroxytetrahydropyrrole HCl;(r)-pyrrolidine-3-ol hydrochloride;CS-B1358;r-(-)-3-pyrrolidinol hydrochloride;3(R)-hydroxypyrrolidine hydrochloride;3-(r)-hydroxypyrrolidine hydrochloride;3r-hydroxypyrrolidine monohydrochloride;AKOS005146004;AKOS005259011;(r)-(+)-3-pyrrolidinol hydrochloride;AC-6381;(R)-3-Pyrrolidinol hydrochloride, 98%;DS-12003;P1140;EN300-69313;A26596;Q-200025;Z1263714129

Suppliers and Price of (R)-3-Hydroxypyrrolidine hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(-)-3-HydroxypyrrolidineHydrochloride
25g
$ 225.00

TCI Chemical
(R)-(-)-3-Pyrrolidinol Hydrochloride >98.0%(T)
25g
$ 335.00

TCI Chemical
(R)-(-)-3-Pyrrolidinol Hydrochloride >98.0%(T)
5g
$ 95.00

SynQuest Laboratories
(3R)-3-Hydroxypyrrolidine hydrochloride
5 g
$ 38.00

SynQuest Laboratories
(3R)-3-Hydroxypyrrolidine hydrochloride
25 g
$ 88.00

Sigma-Aldrich
(R)-3-Pyrrolidinol hydrochloride 98%
10g
$ 161.00

Medical Isotopes, Inc.
(R)-(-)-3-HydroxypyrrolidineHCl
10 g
$ 620.00

Medical Isotopes, Inc.
(R)-(-)-3-HydroxypyrrolidineHCl
25 g
$ 725.00

Matrix Scientific
(R)-3-Hydroxypyrrolidine hydrochloride 95+%
100g
$ 750.00

Matrix Scientific
(R)-3-Hydroxypyrrolidine hydrochloride 95+%
10g
$ 141.00

Total 158 raw suppliers

Chemical Property of (R)-3-Hydroxypyrrolidine hydrochloride Edit

Chemical Property:

Melting Point:104-107 °C(lit.)
Refractive Index:-7.8 ° (C=3.5, MeOH)
Boiling Point:224.7 °C at 760 mmHg
Flash Point:105.8 °C
PSA：32.26000
LogP:0.47140
Storage Temp.:Room temperature.
Solubility.:Soluble in DMSO.
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:123.0450916
Heavy Atom Count:7
Complexity:46.8

Purity/Quality:

99% ^*data from raw suppliers

(R)-(-)-3-HydroxypyrrolidineHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-41-38-37
Safety Statements: 26-36-38

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC1O.Cl
Isomeric SMILES:C1CNC[C@@H]1O.Cl
Uses (R)-(-)-3-Pyrrolidinol hydrochloride is a chiral hydroxy derivative of pyrrlodine used in the preparation of chiral niologically active compounds such as muscarinic receptor antagonists and antimicrobial agents. (R)-3-Hydroxypyrrolidine hydrochloride is used as a darifenacin Intermediate. (R)-3-Pyrrolidinol hydrochloride can be used as a building block to synthesize:Biaryl carboxamide functional groups containing bis-aminopyrrolidine ureas as potential antagonists of the melanin-concentrating hormone receptor-1. Pyrrolidinol based ionic liquids. Optically active 2-tritylpyrrolidine based organocatalysts.

Technology Process of (R)-3-Hydroxypyrrolidine hydrochloride

There total 8 articles about (R)-3-Hydroxypyrrolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%