2H-[2,7]Naphthyridin-1-one hydrobromide

Base Information

• Chemical Name: 2H-[2,7]Naphthyridin-1-one hydrobromide
• CAS No.: 950746-19-7
• Molecular Formula: BrH*C₈H₆N₂O
• Molecular Weight: 227.06
• Hs Code.: 2933990090
• Mol file: 950746-19-7.mol

Synonyms:2H-[2,7]Naphthyridin-1-one hydrobromide;2,7-Naphthyridin-1(2H)-one hydrobroMide

Chemical Property of 2H-[2,7]Naphthyridin-1-one hydrobromide

Chemical Property:

• PSA: 45.75000
• LogP: 1.88120
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2,7-Naphthyridin-1(2H)-onehydrobromide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2H-[2,7]Naphthyridin-1-one hydrobromide

There total 2 articles about 2H-[2,7]Naphthyridin-1-one hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.9%

4-[2-pyrrolidin-1-ylvinyl]nicotinonitrile (950746-11-9) → 2,7-naphthyridin-1-ol hydrobromide (950746-19-7)

Guidance literature:

With hydrogen bromide; trifluoroacetic acid; In acetic acid; at 10 - 50 ℃;

Reference yield:

4-[2-piperidin-1-yl-vinyl]nicotinonitrile (950746-12-0) → 2,7-naphthyridin-1-ol hydrobromide (950746-19-7)

Guidance literature:

4-[2-piperidin-1-yl-vinyl]nicotinonitrile; With hydrogen bromide; trifluoroacetic acid; In acetic acid; at 10 - 50 ℃;

With ethanol;

Reference yield:

2,7-naphthyridin-1-ol hydrobromide (950746-19-7) → 1-chloro-[2,7]naphthyridine (69042-30-4)

Guidance literature:

2,7-naphthyridin-1-ol hydrobromide; With trichlorophosphate; N,N-dimethyl-formamide; for 3h; Reflux;

With ammonia; In water; ethyl acetate; at 15 ℃;

upstream raw materials:

4-[2-pyrrolidin-1-ylvinyl]nicotinonitrile

4-[2-piperidin-1-yl-vinyl]nicotinonitrile

Downstream raw materials:

1-chloro-[2,7]naphthyridine

Refernces