6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Base Information

Chemical Name:6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
CAS No.:615568-38-2
Molecular Formula:C₈H₈N₂O₃
Molecular Weight:180.163
Hs Code.:2934999090
Mol file:615568-38-2.mol

Synonyms:6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one;6-(hydroxyMethyl)-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one;(6-HYDROXYMETHYL)-2H-PYRIDON[3,2-B]-1,4-OXAZIN-3(4H)-ONE;2-b][1;6-(hydroxyMethyl)-2H-pyrido[3

Suppliers and Price of 6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 95+%
1g
$ 1598.00

Alichem
6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
1g
$ 1279.08

Total 6 raw suppliers

Chemical Property of 6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:455.176°C at 760 mmHg
Flash Point:229.082°C
PSA：74.94000
Density:1.42g/cm³
LogP:-0.01010

Purity/Quality:

98%Min ^*data from raw suppliers

6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

There total 7 articles about 6-(Hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: acetic acid 3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-ylmethyl ester

: 615568-38-2
6-(hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Guidance literature:: With sodium hydroxide; water; In 1,4-dioxane; at 20 ℃; for 72h;

Reference yield:

: 443956-11-4
3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-6-carbaldehyde

: 615568-38-2
6-(hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; dichloromethane; at 20 ℃; for 7h; under 750.075 Torr;

Reference yield:

: 15128-82-2
3-hydroxy-2-nitropyridine

: 615568-38-2
6-(hydroxymethyl)-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium methylate / methanol / 0.5 h / 20 °C

1.2: 2 h / 0 °C

2.1: potassium carbonate / acetone / 8 h / Reflux

3.1: acetic acid; iron / 1.5 h / 90 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / water; 1,4-dioxane / 24 h / Reflux

5.1: ozone / dichloromethane; methanol / -71 °C

6.1: hydrogen; palladium 10% on activated carbon / dichloromethane; methanol / 7 h / 20 °C / 750.08 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; hydrogen; sodium methylate; iron; potassium carbonate; ozone; acetic acid; In 1,4-dioxane; methanol; dichloromethane; water; acetone;