(2S)-1-[(4S)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]-2-(diphenylphosphino)-Ferrocene

Base Information

• Chemical Name: (2S)-1-[(4S)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]-2-(diphenylphosphino)-Ferrocene
• CAS No.: 541540-58-3
• Molecular Formula: C₃₂H₂₈FeNOP
• Molecular Weight: 529.401
• Mol file: 541540-58-3.mol

Synonyms:(2S)-1-[(4S)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]-2-(diphenylphosphino)-Ferrocene

Chemical Property of (2S)-1-[(4S)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]-2-(diphenylphosphino)-Ferrocene

Chemical Property:

• PSA: 35.18000
• LogP: 4.78220

Purity/Quality:

97%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S)-1-[(4S)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]-2-(diphenylphosphino)-Ferrocene

There total 1 articles about (2S)-1-[(4S)-4,5-dihydro-4-(phenylMethyl)-2-oxazolyl]-2-(diphenylphosphino)-Ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-3,5-dihydrodinaphtho[2,1-c:1',2'-e]selenepin 4-oxide (297163-59-8) + rac-[2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine (870197-45-8,544702-56-9,541540-58-3,163169-14-0) → [2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine (541540-58-3,870197-45-8,544702-56-9,163169-14-0) + [2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine oxide*H2O

Guidance literature:

With phenol; In tetrachloromethane; under N2; soln. of selenoxide and C6H5OH in CCl4 stirred at room temp. for 15 min, added phosphine in CCl4, stirred at room temp. for 24 h; chromy. (SiO2), enantiomeric excess of phosphine and phosphine oxide 9% and 22% respectively; elem. anal. for phosphine oxide;

DOI:10.1246/bcsj.76.381

Reference yield:

(R)-3,5-dihydrodinaphtho[2,1-c:1',2'-e]selenepin 4-oxide (297163-59-8) + rac-[2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine (870197-45-8,544702-56-9,541540-58-3,163169-14-0) → [2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine (541540-58-3,870197-45-8,544702-56-9,163169-14-0) + [2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine oxide*H2O

Guidance literature:

With phenol; In tetrachloromethane; under N2; soln. of selenoxide and C6H5OH in CCl4 stirred at room temp. for 15 min, added phosphine in CCl4, stirred at room temp. for 24 h; chromy. (SiO2), enantiomeric excess of phosphine and phosphine oxide 9% and 22% respectively; elem. anal. for phosphine oxide;

DOI:10.1246/bcsj.76.381

upstream raw materials:

(R)-3,5-dihydrodinaphtho[2,1-c:1',2'-e]selenepin 4-oxide

rac-[2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine

Downstream raw materials:

[2-(4-benzyl-2-oxazoline-2-yl)ferrocenyl]diphenylphosphine

Refernces