1-Formyl-1-(triisopropylsilyloxy)cyclopropane

Base Information

Chemical Name:1-Formyl-1-(triisopropylsilyloxy)cyclopropane
CAS No.:220705-67-9
Molecular Formula:C13H26O2Si
Molecular Weight:242.42984
Hs Code.:
DSSTox Substance ID:DTXSID30573171
Wikidata:Q82461773
Mol file:220705-67-9.mol

Synonyms:1-Formyl-1-(triisopropylsilyloxy)cyclopropane;220705-67-9;1-tri(propan-2-yl)silyloxycyclopropane-1-carbaldehyde;1-Flormyl-1-(triisopropylsilyloxy)cyclopropane;1-((Triisopropylsilyl)oxy)cyclopropane-1-carbaldehyde;starbld0002730;1-(Triisopropylsilyloxy)cyclopropylformaldehyde;DTXSID30573171;J-014465;1-{[Tri(propan-2-yl)silyl]oxy}cyclopropane-1-carbaldehyde

Suppliers and Price of 1-Formyl-1-(triisopropylsilyloxy)cyclopropane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Formyl-1-(triisopropylsilyloxy)cyclopropane
5 mg
$ 275.00

TRC
1-Formyl-1-(triisopropylsilyloxy)cyclopropane
1mg
$ 85.00

Total 2 raw suppliers

Chemical Property of 1-Formyl-1-(triisopropylsilyloxy)cyclopropane

Chemical Property:

PSA：26.30000
LogP:3.91000
Solubility.:Dichloromethane
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:242.170206602
Heavy Atom Count:16
Complexity:233

Purity/Quality:

97% ^*data from raw suppliers

1-Formyl-1-(triisopropylsilyloxy)cyclopropane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)[Si](C(C)C)(C(C)C)OC1(CC1)C=O
Uses 1-Formyl-1-(triisopropylsilyloxy)cyclopropane (cas# 220705-67-9) is a compound useful in organic synthesis.

Technology Process of 1-Formyl-1-(triisopropylsilyloxy)cyclopropane

There total 3 articles about 1-Formyl-1-(triisopropylsilyloxy)cyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 205756-60-1
(1-triisopropylsilanyloxy-cyclopropyl)-methanol

: 220705-67-9
1-triisopropylsilanyloxy-cyclopropanecarbaldehyde

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane;
DOI:10.1016/S0960-894X(01)00012-9

Reference yield:

: 205756-59-8
methyl 1-((triisopropylsilyl)oxy)cyclopropane-1-carboxylate

: 220705-67-9
1-triisopropylsilanyloxy-cyclopropanecarbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: Dibal / -78 °C

2: oxalyl chloride; DMSO; NEt₃ / CH₂Cl₂

With oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In dichloromethane;
DOI:10.1016/S0960-894X(01)00012-9

Reference yield:

: 13154-24-0
triisopropylsilyl chloride

: 220705-67-9
1-triisopropylsilanyloxy-cyclopropanecarbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / 20 h / 35 °C

2.1: diisobutylaluminium hydride / toluene / -78 - 0 °C / Inert atmosphere

3.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / Inert atmosphere

3.2: -78 - 0 °C / Inert atmosphere

With 1H-imidazole; oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jacs.0c08089