205756-59-8 Usage
Uses
Used in Organic Synthesis:
1-(Triisopropylsilyloxy)cyclopropylcarboxylic Acid Methyl Ester is used as a synthetic building block for the creation of more complex organic molecules. Its triisopropylsilyloxy group and cyclopropylcarboxylic acid methyl ester moiety provide a versatile platform for further chemical modifications and functionalization, making it a valuable asset in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(Triisopropylsilyloxy)cyclopropylcarboxylic Acid Methyl Ester is used as a key intermediate in the development of novel drug candidates. Its unique chemical properties allow for the design and synthesis of new molecules with potential therapeutic applications, contributing to the advancement of drug discovery and development.
Used in Agrochemical Industry:
1-(Triisopropylsilyloxy)cyclopropylcarboxylic Acid Methyl Ester is also employed in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its chemical versatility enables the development of innovative compounds with improved efficacy, selectivity, and environmental compatibility.
Used in Specialty Chemicals:
In the specialty chemicals sector, 1-(Triisopropylsilyloxy)cyclopropylcarboxylic Acid Methyl Ester is utilized for the synthesis of various high-value compounds, such as advanced materials, dyes, and additives. Its unique properties and reactivity contribute to the development of new products with enhanced performance and functionality.
Check Digit Verification of cas no
The CAS Registry Mumber 205756-59-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,5,7,5 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 205756-59:
(8*2)+(7*0)+(6*5)+(5*7)+(4*5)+(3*6)+(2*5)+(1*9)=138
138 % 10 = 8
So 205756-59-8 is a valid CAS Registry Number.
205756-59-8Relevant academic research and scientific papers
Experimental and Computational Studies on Rh(I)-Catalyzed Reaction of Siloxyvinylcyclopropanes and Diazoesters
Feng, Sheng,Wang, Kang,Ping, Yifan,Wang, Jianbo
supporting information, p. 21032 - 21039 (2020/12/21)
The Rh(I)-catalyzed reaction of siloxyvinylcyclopropanes and diazoesters leads to the formation of siloxyvinylcyclobutane and 1,4-diene derivatives. With [Rh(cod)Cl]2 as the catalyst, the formation of 1,4-diene was favored over the formation of siloxyvinylcyclobutane. By changing the catalyst to [Rh(cod)2OTf], siloxyvinylcyclobutane derivatives are formed with excellent chemoselectivities and in moderate to good yields. The alkene products are also obtained as single E configured isomers. A detailed mechanism for this transformation is proposed on the basis of mechanistic experiments and DFT calculations. The effect of catalysts on the chemoselectivity of these reactions is also examined computationally.
Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz
Markwalder, Jay A.,Christ, David D.,Mutlib, Abdul,Cordova, Beverly C.,Klabe, Ronald M.,Seitz, Steven P.
, p. 619 - 622 (2007/10/03)
Studies on the biotransformation of the clinically important non-nucleoside reverse transcriptase inhibitor efavirenz have shown that oxidation and secondary conjugation are important components of the processing of this molecule in vivo. We have synthesized metabolites of efavirenz to confirm their structure and to evaluate their activity as antivirals.
