(2Z)-2-Fluoro-1-phenylpent-2-en-1-one

Base Information

Chemical Name:(2Z)-2-Fluoro-1-phenylpent-2-en-1-one
CAS No.:41343-04-8
Molecular Formula:C₁₁H₁₁FO
Molecular Weight:178.206
Hs Code.:
DSSTox Substance ID:DTXSID20567483
Nikkaji Number:J498.541I
Wikidata:Q82453379
Mol file:41343-04-8.mol

Synonyms:41343-04-8;DTXSID20567483;(2Z)-2-Fluoro-1-phenylpent-2-en-1-one;2-Penten-1-one,2-fluoro-1-phenyl-,(Z)-(9ci)

Suppliers and Price of (2Z)-2-Fluoro-1-phenylpent-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2Z)-2-Fluoro-1-phenylpent-2-en-1-one

Chemical Property:

PSA：17.07000
LogP:3.13270
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:178.079393132
Heavy Atom Count:13
Complexity:202

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC=C(C(=O)C1=CC=CC=C1)F
Isomeric SMILES:CC/C=C(/C(=O)C1=CC=CC=C1)\F

Technology Process of (2Z)-2-Fluoro-1-phenylpent-2-en-1-one

There total 6 articles about (2Z)-2-Fluoro-1-phenylpent-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 138042-63-4
4-fluoro-1-phenyl-2-(phenylsulfinyl)-1-pentanone

: 41343-04-8
(Z)-2-fluoro-1-phenyl-2-penten-1-one

Guidance literature:: In benzene; for 0.416667h; Heating;
DOI:10.1246/bcsj.65.2800

Reference yield:

: 100-52-7
benzaldehyde

: 41343-04-8
(Z)-2-fluoro-1-phenyl-2-penten-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2.) THF, -78 deg C, 5 min

2: oxalyl chloride, dimethyl sulfoxide / CH₂Cl₂ / 0.25 h / -60 °C

3: 75 percent / benzene / 0.42 h / Heating

With oxalyl dichloride; dimethyl sulfoxide; lithium diisopropyl amide; In dichloromethane; benzene;
DOI:10.1246/bcsj.65.2800

Reference yield:

: 138042-52-1
2-Benzenesulfinyl-2-fluoro-1-phenyl-pentan-1-ol

: 41343-04-8
(Z)-2-fluoro-1-phenyl-2-penten-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride, dimethyl sulfoxide / CH₂Cl₂ / 0.25 h / -60 °C

2: 75 percent / benzene / 0.42 h / Heating

With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; benzene;
DOI:10.1246/bcsj.65.2800