Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-alpha-D-glucopyranosyl) ester

Base Information

• Chemical Name: Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-alpha-D-glucopyranosyl) ester
• CAS No.: 244226-72-0
• Molecular Formula: C16H27N3O14P2
• Molecular Weight: 547.35
• Mol file: 244226-72-0.mol

Synonyms:Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-alpha-D-glucopyranosyl) ester

Chemical Property of Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-alpha-D-glucopyranosyl) ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-alpha-D-glucopyranosyl) ester

There total 1 articles about Thymidine 5'-(trihydrogen diphosphate) P'-(4-amino-4,6-dideoxy-alpha-D-glucopyranosyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

thymidine 5'-phosphate (365-07-1,15108-71-1,60363-32-8,96744-88-6,132696-16-3,143838-77-1) + α-D-glucopyranosyl-1-phosphate (59-56-3,27251-84-9,63779-58-8,262856-84-8) → thymidine 5'-diphospho-4-amino-4,6-dideoxy-α-D-glucopyranose (244226-72-0)

Guidance literature:

With L-glutamic acid; pyridoxal 5'-phosphate; Streptomyces sp. GERI-155 GerB; dTDP-glucose 4,6-dehydratase; In various solvent(s); at 37 ℃; for 4.5h; pH=7.5; Enzymatic reaction;

DOI:10.1016/j.carres.2007.04.007

Reference yield:

3,4-dichlorophenol (95-77-2) + thymidine 5'-diphospho-4-amino-4,6-dideoxy-α-D-glucopyranose (244226-72-0) → C12H15Cl2NO4

Guidance literature:

With glycosyltransferases YdhE bacillus licheniformi; magnesium chloride; In dimethyl sulfoxide; at 30 ℃; for 3h; pH=8.8; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/acs.orglett.9b03040

Reference yield:

3,4-dichlorothiophenol (5858-17-3) + thymidine 5'-diphospho-4-amino-4,6-dideoxy-α-D-glucopyranose (244226-72-0) → C12H15Cl2NO3S

Guidance literature:

With glycosyltransferases YdhE bacillus licheniformi; magnesium chloride; In dimethyl sulfoxide; at 30 ℃; for 3h; pH=8.8; Reagent/catalyst; Enzymatic reaction;

DOI:10.1021/acs.orglett.9b03040

upstream raw materials:

thymidine 5'-phosphate

α-D-glucopyranosyl-1-phosphate